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Commonly Used Brand Name(s)Dysport
Therapeutic ClassificationsMusculoskeletal Agent
Pharmacologic ClassificationsBotulinum Toxin Type A
- Blackbox Warning
- Proper Use
- Before Using
- Breast Feeding
- Drug Interactions
- Other Interactions
- Other Medical Problems
AbobotulinumtoxinA is used to treat the abnormal head position and neck pain that result from cervical dystonia (severe muscle spasms of the neck). This medicine is also used cosmetically to improve the appearance of deep facial lines or wrinkles between the eyebrows (glabellar lines). It is also used to treat upper and lower limb spasms.
AbobotulinumtoxinA is a botulinum toxin A product. It works on the nervous system to relax the muscles.
This medicine is available only with your doctor's prescription and will be administered by your doctor.
Your doctor will give you this medicine in a hospital or clinic. This medicine is given as a shot into one of your muscles.
This medicine should come with a Medication Guide. Read and follow these instructions carefully. Ask your doctor or pharmacist if you have any questions.
Your doctor will only use abobotulinumtoxinA (Dysport®) to treat your condition. Other botulinum toxin products may not work the same way and require a different dose. Tell your doctor if you have received botulinum toxin for any reason in the last 4 months.
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:
Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Appropriate studies have not been performed on the relationship of age to the effects of abobotulinumtoxinA in children with cervical dystonia or upper limb spasms, and in children younger than 2 years of age with lower limb spasms. Safety and efficacy have not been established.
Use of abobotulinumtoxinA to treat glabellar lines is not recommended in children.
Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of abobotulinumtoxinA in the elderly. However, elderly patients are more sensitive to the effects of this medicine than younger adults and are more likely to have falls, weakness, or side effects related to the eyes, which may require caution in patients receiving abobotulinumtoxinA for lower limb spasticity and glabellar lines.
There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.
Other Medical ProblemsTOP
The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:
- Amyotrophic lateral sclerosis (Lou Gehrig's disease) or
- Dermatochalasis (a skin problem) or
- Lambert-Eaton syndrome (nerve-muscle disorder) or
- Motor neuropathy (muscle and nerve problem) or
- Myasthenia gravis (severe muscle weakness) or
- Sebaceous skin, thick (oily or fatty skin) or
- Surgery on the face, history of—May increase risk for more serious side effects.
- Breathing problems (eg, asthma, emphysema) or
- Dysphagia (trouble swallowing) or
- Ptosis (droopy eyelid)—Use with caution. May make these conditions worse.
- Cow's milk protein allergy, history of or
- Infection at the injection site—Should not be used in patients with these conditions.
It is very important that your doctor check your progress at regular visits. This will allow your doctor to see if the medicine is working properly and to decide if you should continue to receive it.
Serious muscle reactions have occurred within hours to weeks after receiving this medicine. If you start to have muscle weakness, loss of bladder control, or trouble with swallowing, talking, or breathing, call your doctor right away. In some patients, these problems could be life-threatening and may require immediate treatment in a hospital or clinic.
This medicine may make your muscles weak and cause vision problems. Avoid driving, using machines, or doing anything else that could be dangerous if you feel weak or are not able to see well.
This medicine is made from donated human blood. Some human blood products have transmitted certain viruses to people who have received them, although the risk is low. Human donors and donated blood are both tested for viruses to keep the transmission risk low. Talk with your doctor if you have concerns about this risk.
Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.