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Pain Medications

Find prices and information on Pain medications.

Read our guide toPain

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Key takeaways

Pain medications are used to treat acute pain, such as post-surgical pain, and chronic pain, such as from arthritis. They work in various ways to relieve pain and reduce inflammation. Common classes include opioids, nonsteroidal anti-inflammatory drugs (NSAIDs), and acetaminophen (Tylenol). Opioids like hydrocodone / acetaminophen and oxycodone / acetaminophen (Percocet) are available as oral pills. NSAIDs, such as ibuprofen (Advil, Motrin) and naproxen (Aleve, Naprosyn), are typically taken as oral tablets or liquid.These options provide different ways to help manage your pain effectively.

Prices for popular Pain medications

Viewing 25 of 214 medications

Hycet (hydrocodone / acetaminophen)

as low as$8

View otherOpioid / Acetaminophen Combinations

Hydrocodone/acetaminophen (Vicodin, Lorcet, Lortab, Norco, Xodol, Hycet) is inexpensive drug used to treat moderate to severe pain. It is more popular than comparable drugs. It is available in multiple generic and brand versions. Generic hydrocodone/acetaminophen is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.

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Xodol (hydrocodone / acetaminophen)

as low as$8

View otherOpioid / Acetaminophen Combinations

Hydrocodone/acetaminophen (Vicodin, Lorcet, Lortab, Norco, Xodol, Hycet) is inexpensive drug used to treat moderate to severe pain. It is more popular than comparable drugs. It is available in multiple generic and brand versions. Generic hydrocodone/acetaminophen is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.

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ibuprofen

as low as$8

View otherNSAIDs

Ibuprofen is an NSAID used to treat fever and pain from arthritis, menstrual cramps, and muscular aches. It works by reducing inflammation. Ibuprofen is a generic medication, and is available both over-the-counter and by prescription depending on the strength. Prescription Motrin had the same active ingredient, but has been discontinued. Over-the-counter brands include Advil and Motrin IB. Ibuprofen should be used only when needed as it may increase risk of stroke or heart attack and long term use can cause stomach bleeding and ulcers.

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Ultram (tramadol)

as low as$8

View otherOpioids

Tramadol (Ultram) is an inexpensive drug used to treat moderate to severe pain in adults. This drug is more popular than comparable drugs. It is available in generic and brand versions. Generic tramadol is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.

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Endocet (oxycodone / acetaminophen)

as low as$7

View otherOpioid / Acetaminophen Combinations

Oxycodone/acetaminophen (Endocet, Percocet, prolate, nalocet) is a moderately priced drug used to treat moderate to severe pain.This drug is more popular than comparable drugs. It is available in multiple brand and generic versions. Generic oxycodone/acetaminophen is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.

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Percocet (oxycodone / acetaminophen)

as low as$7

View otherOpioid / Acetaminophen Combinations

Oxycodone/acetaminophen (Endocet, Percocet, prolate, nalocet) is a moderately priced drug used to treat moderate to severe pain.This drug is more popular than comparable drugs. It is available in multiple brand and generic versions. Generic oxycodone/acetaminophen is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.

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Roxicodone (oxycodone)

as low as$7

View otherOpioids

Oxycodone (Roxicodone) is a moderately priced drug used to treat moderate to severe pain. This drug is slightly more popular than comparable drugs. It is available in both generic and brand versions. Generic oxycodone is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.

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aspirin

as low as$3

View otherNSAIDs

Aspirin is an inexpensive drug used to treat mild pain and fever. It is also used as directed by a doctor to prevent and to treat heart attacks, to prevent strokes and blood clots, and to treat arthritis or inflammation. Aspirin is only available as an over-the-counter medication.

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Celebrex (celecoxib)

as low as$10

View otherNSAIDs

Celecoxib (Celebrex) is a moderately priced drug used to treat arthritis and ankylosing spondylitis. It may also be used for pain or painful monthly periods. This drug is slightly more popular than comparable drugs. It is available in brand and generic form. Generic celecoxib is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.

Sprix (ketorolac)

as low as$14

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KETOROLAC treats short-term moderate to severe pain. It works by decreasing inflammation. It belongs to a group of medications called NSAIDs.

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Anaprox DS (naproxen)

as low as$10

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Naproxen (Naprosyn, Anaprox DS) is an inexpensive drug used to reduce swelling and treat pain. It is also used for painful joint and muscular problems such as arthritis, tendinitis, bursitis, and gout. It is slightly more popular than comparable drugs. It is available in multiple generic and brand versions. Generic naproxen is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.

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Naprosyn (naproxen)

as low as$10

View otherNSAIDs

Naproxen (Naprosyn, Anaprox DS) is an inexpensive drug used to reduce swelling and treat pain. It is also used for painful joint and muscular problems such as arthritis, tendinitis, bursitis, and gout. It is slightly more popular than comparable drugs. It is available in multiple generic and brand versions. Generic naproxen is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.

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Xylocaine (lidocaine)

as low as$13

View otherLocal Anesthetics

Lidocaine (Lidoderm, Lidocaine) is an inexpensive drug used to prevent and treat pain from some procedures. This drug is more popular than comparable drugs. It is available in multiple generic and brand versions. Generic lidocaine is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.

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diphenhydramine / zinc acetate

as low as$4

View otherLocal Analgesics

Diphenhydramine/zinc acetate is used to treat pain and itching due to insect bites, skin irritation, and rashes. It is available in generic and brand versions. It may be covered by your Medicare or insurance plan, but some pharmacy coupons or cash prices could help offset the cost.

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Acephen (acetaminophen)

as low as$4

View otherAcetaminophens

ACETAMINOPHEN treats mild to moderate pain. It may also be used to reduce fever.

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Advil (ibuprofen non-prescription)

as low as$4

View otherNSAIDs

IBUPROFEN treats mild to moderate pain, inflammation, or arthritis. It may also be used to reduce fever. It belongs to a group of medications called NSAIDs.

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camphor / menthol / methyl salicylate

as low as$4

View otherLocal Analgesics

CAMPHOR; MENTHOL; METHYL SALICYLATE relieves minor pain in your muscles and joints. It works by making your skin feel warm or cool, which blocks pain signals going to the brain. It also decreases inflammation. This product contains a salicylate.

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Mapap (acetaminophen)

as low as$4

View otherAcetaminophens

ACETAMINOPHEN treats mild to moderate pain. It may also be used to reduce fever.

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Mapap Extra Strength (acetaminophen extra strength)

as low as$4

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ACETAMINOPHEN treats mild to moderate pain. It may also be used to reduce fever.

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Motrin IB (ibuprofen non-prescription)

as low as$4

View otherNSAIDs

Motrin IB is an NSAID that is used to treat fever and minor aches and pains. It works by reducing inflammation. Motrin IB is available over the counter, and as generic ibuprofen. Other brands include Advil.

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Q-Pap (acetaminophen)

as low as$4

View otherAcetaminophens

ACETAMINOPHEN treats mild to moderate pain. It may also be used to reduce fever.

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Sudafed PE Pressure and Pain (acetaminophen / phenylephrine)

as low as$4

View otherAcetaminophen Combinations

Sudafed PE Pressure And Pain is part of the Acetaminophen Combinations class and treats Pain, Nasal Congestion and Fever. Acetaminophen is combined with other active ingredients like diphenhydramine and dextromethorphan to relieve cough, cold, allergy, and insomnia symptoms along with treating pain, menstrual pain, and fever. Sudafed PE Pressure And Pain is only available as a brand name drug.

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Tylenol (acetaminophen)

as low as$4

View otherAcetaminophens

ACETAMINOPHEN treats mild to moderate pain. It may also be used to reduce fever.

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Tylenol Extra Strength (acetaminophen extra strength)

as low as$4

View otherAcetaminophens

ACETAMINOPHEN treats mild to moderate pain. It may also be used to reduce fever.

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Silapap

as low as$4

View otherAcetaminophens

ACETAMINOPHEN treats mild to moderate pain. It may also be used to reduce fever.

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Disclaimer: Popularity is based on total prescriptions for the brand and generic versions of each drug, regardless of the condition being treated. Some drugs are prescribed for multiple conditions.

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