Opioid agonist/antagonists are used to treat opioid use disorder and manage chronic pain, among other These medications work by partially activating opioid receptors in your brain while also blocking other opioids from attaching to these receptors. This helps to reduce opioid cravings and withdrawal symptoms in opioid use disorder. Opioid-agonist-antagonists come in different forms, including oral tablets, films, and injections. Examples include buprenorphine/naloxone (Suboxone), buprenorphine (Butrans, Suboclade), and pentazocine/naloxone. You can choose the form that best fits your needs.