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Xalatan vs. Brimonidine

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Latanoprost (Xalatan) and Alphagan P (brimonidine) are both prescription eye drops used to lower eye pressure in conditions like glaucoma and ocular hypertension, but they work differently and have distinct usage patterns. Latanoprost is a prostaglandin that helps fluid drain from the eye and is typically used once daily in the evening. In contrast, Alphagan P is an alpha-2 agonist that reduces fluid production in the eye and is applied three times a day. Latanoprost can cause changes in eye color and eyelash growth, while Alphagan P is more likely to cause dry mouth, headaches, and drowsiness. Latanoprost needs refrigeration before opening, whereas Alphagan P can be stored at room temperature. Both medications require the removal of contact lenses before use, but latanoprost is known for causing less eye irritation compared to Alphagan P.

Latanoprost

(Xalatan)

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Alphagan P

(brimonidine)

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Summary for Xalatan

Prescription only

Latanoprost (Xalatan) is an eye drop medication. It's used in adults to treat conditions related to high pressure in the eye, such as glaucoma. It works as a prostaglandin to help with high eye pressure. The typical dosage is 1 drop in the affected eye(s) once each night. Side effects include feeling like there's something in the eye, burning, and stinging. Unopened bottles need to be refrigerated. But once opened, you keep the medication at room temperature. Latanoprost (Xalatan) is available as a brand-name and generic medication.

Indications for Xalatan

Pros and Cons for Xalatan

Pros

Cons

  • Can permanently change the color of your eye
  • Need to take out any soft contact lenses before using

Common Side Effects for Xalatan

  • Feeling like there's something inside the eye (13%)
  • Stinging (9%)
  • Eye redness (8%)
  • Blurry vision (8%)
  • Itchy eye (8%)
  • Burning (7%)
  • Changes in eye color (7%)

Warnings for Xalatan

  • Darker eyes or eyelids
  • Eyelash changes
  • Eye inflammation
  • Swelling of the retina (macular edema)
  • Caution use in people with a history of a herpes eye infection
  • Risk of bacterial eye infection when using contaminated medication
  • Don't use while wearing soft contact lenses

Summary for Brimonidine

Prescription only

Alphagan P (brimonidine) is a prescription eye drop that helps lower pressure in the eye and treats glaucoma. It's typically applied three times a day. Some common side effects include blurry vision, slight stinging in the eyes, and headaches. Alphagan P (brimonidine) is available as both a brand name and a generic medication.

Indications for Brimonidine

High pressure in the eye caused by:

Pros and Cons for Brimonidine

Pros

  • Good at treating high eye pressure
  • Start working to lower eye pressure in as quickly as 1 hour
  • Can be stored at room temperature

Cons

  • Can cause dry mouth, headache, and drowsiness
  • Applied 3 times daily
  • Must take out contact lenses out before applying

Common Side Effects for Brimonidine

  • Dry mouth (up to 30%)
  • Red eye (up to 30%)
  • Eye burning and stinging (up to 30%)
  • Headache (up to 30%)
  • Blurry vision (up to 30%)
  • Feeling like there's something in your eye (up to 30%)
  • Sleepiness (up to 30%)
  • Small white patches on the inside of the eyelids (up to 30%)
  • Allergic reactions in the eye (up to 30%)
  • Itchy eyes (up to 30%)

Warnings for Brimonidine

  • Risk of worsening of low blood flow
  • Risk of infections (from contamination)
  • No soft contact lenses
  • Only use in the eye

Prices with our coupons for Xalatan vs. Brimonidine

Price Card Drug Icon
Latanoprost1 eye dropper / 2.5ml of 0.005%
$10.20$88.01
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Price Card Drug Icon
Brimonidine1 eye dropper / 5ml of 0.2%
$8.59$33.06
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