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Vyzulta vs. Latanoprost

Latanoprostene bunod ophthalmic solution, also known by its brand name Vyzulta, is the only prostaglandin that also releases nitric oxide along with latanoprost acid, working in two ways to help lower eye pressure. This eye drop medication is used to treat conditions related to high pressure in the eye, such as glaucoma. Vyzulta (latanoprostene bunod) is approved for people 17 years of age and older. It's given as a drop into the affected eye(s) once daily in the evening. Bottles should be refrigerated, but they can be stored at room temperature for up to 8 weeks after opening. Side effects include eye redness and eye pain.

• Lowering pressure in the eye in people with ocular hypertension (high pressure in the eye) or open-angle glaucoma

• Red eyes (6%)
• Eye irritation (4%)
• Eye pain (3%)
• Eye pain after placing the drop into the eye (2%)

• Darker eyes, eyelashes, or eyelids
• Eyelash changes
• Eye inflammation
• Swelling of the retina (macular edema)
• Risk for bacterial infection in the eye when using contaminated medication
• Don't use while wearing soft contact lenses

Latanoprost (Xalatan) is an eye drop medication. It's used in adults to treat conditions related to high pressure in the eye, such as glaucoma. It works as a prostaglandin to help with high eye pressure. The typical dosage is 1 drop in the affected eye(s) once each night. Side effects include feeling like there's something in the eye, burning, and stinging. Unopened bottles need to be refrigerated. But once opened, you keep the medication at room temperature. Latanoprost (Xalatan) is available as a brand-name and generic medication.

• Lowering pressure in the eye in people with open-angle glaucoma or ocular hypertension (high pressure in the eye)

• Feeling like there's something inside the eye (13%)
• Stinging (9%)
• Eye redness (8%)
• Blurry vision (8%)
• Itchy eye (8%)
• Burning (7%)
• Changes in eye color (7%)

• Darker eyes or eyelids
• Eyelash changes
• Eye inflammation
• Swelling of the retina (macular edema)
• Caution use in people with a history of a herpes eye infection
• Risk of bacterial eye infection when using contaminated medication
• Don't use while wearing soft contact lenses