Key takeaways
Diclofenac (Voltaren) and tramadol (Ultram, Conzip) are both prescription medications used to treat pain, but they belong to different drug classes and work in different ways. Diclofenac is a non-steroidal anti-inflammatory drug (NSAID) that helps reduce pain and swelling by blocking certain proteins in your body. It is available in various formulations, including tablets, capsules, and powder, and is typically used for conditions like arthritis, migraines, and menstrual cramps. Tramadol, on the other hand, is an opioid that changes the way your brain perceives pain and also increases levels of serotonin and norepinephrine. It is used when non-opioid medications aren't effective enough. Unlike diclofenac, tramadol is a controlled substance due to its potential for misuse and dependency. Diclofenac is not recommended for use in pregnancy, especially after the second trimester, while tramadol is generally not recommended during pregnancy or breastfeeding due to risks to the baby. Both medications have serious side effects, but tramadol has additional risks like dangerously slow breathing and serotonin syndrome.
