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Vimpat vs. Aptiom

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Vimpat (lacosamide) and Aptiom (eslicarbazepine) are both oral prescription antiepileptic medications used to treat seizures, but they have some key differences. Vimpat can be taken twice daily for partial-onset seizures and as add-on treatment for primary generalized tonic-clonic (PGTC) seizures, whereas Aptiom is taken once a day and is only approved for partial-onset seizures. Both medications are available as low-cost generics which can be used in children as young as 4 years old. However, brand-name Vimpat can be used in children as young as 1 month for the treatment of partial-onset seizures. Vimpat is available as a tablet and oral solution, whereas Aptiom is only available in tablet form, but can be crushed if you have difficulty swallowing. Both medications can cause dizziness and other side effects, but Aptiom has a higher risk of causing low sodium levels in your blood. Unlike Aptiom, Vimpat is a Schedule V controlled substance, meaning it has a potential for misuse and dependence.

Lacosamide

(Vimpat)

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Aptiom

(eslicarbazepine)

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Summary for Vimpat

Prescription only

Lacosamide (Vimpat) is an antiepileptic. People 1 month and older can take it on its own or with other antiepileptics for partial-onset seizures (also called focal aware seizures). It's also an add-on medication for people 4 years and older who have primary generalized tonic-clonic (PGTC) seizures (or grand mal seizures). Lacosamide (Vimpat) comes as tablets and an oral solution that's taken by mouth twice a day. It's also available as an injection that's used in the hospital. Side effects include dizziness, headache, and nausea. Lacosamide (Vimpat) comes as both brand-name and generic versions, but it's a controlled substance.

Indications for Vimpat

Pros and Cons for Vimpat

Pros

  • Can take with other seizure medications
  • Available as a tablet and oral solution
  • Okay for children 1 month of age and older with partial-onset seizures and children 4 years and older with PGTC seizures

Cons

Common Side Effects for Vimpat

  • Dizziness (31%)
  • Headache (13%)
  • Nausea (11%)
  • Double vision (11%)
  • Vomiting (9%)
  • Tiredness (9%)
  • Blurred vision (8%)
  • Problems with movement or coordination (8%)
  • Sleepiness (7%)
  • Tremor (7%)

Warnings for Vimpat

  • Risk of suicidal thoughts and behavior
  • Dizziness and problems with controlling movements
  • Abnormal heartbeat
  • Withdrawal seizures
  • Allergic reactions
  • Caution use in people with phenylketonuria (PKU) - oral solution only

Summary for Aptiom

Prescription only

Aptiom (eslicarbazepine) helps control seizures if you have partial-onset epilepsy. It can be used in people aged 4 years and older, but it interacts with some other medications and can be expensive if not covered by insurance.

Indications for Aptiom

  • Partial-onset seizures

Pros and Cons for Aptiom

Pros

  • Can be used on its own, or with other seizure medications for better seizure control
  • Convenient, taken once daily
  • Tablets can be crushed (doesn't come in liquid form)

Cons

  • Causes dizziness, headache, and vision problems quite often
  • Can't take if you're allergic to oxcarbazepine (Trileptal)
  • Brand name only, so it can be more expensive than other alternatives

Common Side Effects for Aptiom

  • Dizziness (20-28%)
  • Sleepiness (11-18%)
  • Headache (13-15%)
  • Nausea (10-16%)
  • Double vision (9-11%)
  • Vomiting (6-10%)
  • Tiredness (4-7%)
  • Blurry vision (5-6%)
  • Difficulty with movement or coordination (4-6%)
  • Feeling like the room is spinning (2-6%)
  • Shakiness (tremor, 2-4%)

Warnings for Aptiom

  • Suicidal thoughts or behavior
  • Severe allergic reactions
  • Low sodium levels
  • Difficulty with movement, concentration, and vision
  • Withdrawal seizures
  • Liver injury

Prices with our coupons for Vimpat vs. Aptiom

Price Card Drug Icon
Vimpat60 tablets / 200mg
$1,143.02$1,498.76
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Eslicarbazepine30 tablets / 800mg
$67.96$1,247.04
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