Key takeaways
Icosapent ethyl (Vascepa) and omega-3-acid ethyl esters (Lovaza) are both used to lower triglyceride levels in adults, but they have some key differences. Vascepa contains only one type of omega-3 fatty acid, while Lovaza contains two types: eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). Vascepa is typically taken twice a day, whereas Lovaza can be taken once or twice a day. Vascepa is also used to lower the risk of heart problems in people taking statins who have high triglycerides and other risk factors, while Lovaza is mainly used for very high triglyceride levels. Common side effects of Vascepa include muscle and bone pain, while Lovaza often causes burping and changes in taste. Both medications are available as lower-cost generics and should be taken with food.
