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Toprol XL vs. Lopressor

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Metoprolol succinate (Toprol XL) and metoprolol tartrate (Lopressor) are both beta blockers used to treat high blood pressure and chest pain (angina). However, they have some important differences. Metoprolol succinate (Toprol XL) is an extended-release medication taken once daily and is also approved to lower the risk of hospitalization and death in people with heart failure. In contrast, metoprolol tartrate (Lopressor) is a short-acting medication taken twice daily and is approved to lower the risk of death after a heart attack. Both medications can cause side effects like tiredness, dizziness, and diarrhea. Also, both medications can hide symptoms of low blood sugar, so you should be aware of that if you have diabetes. Both medications are available as a lower-cost generic.

Metoprolol succinate

(Toprol XL)

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Metoprolol tartrate

(Lopressor)

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Summary for Toprol XL

Prescription only

Metoprolol succinate (Toprol XL) is used to treat hypertension and to control chronic (long-term) chest pain. It's also used to lower the risk for hospitalization and death in people with heart failure. Metoprolol succinate (Toprol XL) is the extended-release version of metoprolol tartrate (Lopressor), but keep in mind the two versions don't treat the exact same conditions. And because metoprolol succinate (Toprol XL) is longer-acting, it's taken by mouth typically taken just once daily. Some common side effects of metoprolol succinate (Toprol XL) include tiredness or dizziness.

Indications for Toprol XL

  • High blood pressure
  • Chest pain (angina)
  • Lower the risk of hospitalization and death in heart failure

Pros and Cons for Toprol XL

Pros

  • A first-choice option to prevent chest pains (angina)
  • A first-choice option for heart failure
  • Only needs to be taken once a day
  • Available as capsules (Kapspargo) that can be opened and sprinkled on soft foods, good for people who've trouble swallowing pills

Cons

Common Side Effects for Toprol XL

  • Tiredness
  • Dizziness
  • Depression
  • Diarrhea
  • Trouble catching your breath
  • Drop in heart rate
  • Rash

Please note: The side effects above occurred in 2% or more of people taking metoprolol succinate (Toprol XL).

Warnings for Toprol XL

  • Heart problems after suddenly stopping the medication
  • Worsened symptoms of heart failure
  • Risk of difficulty breathing
  • Rise in blood pressure in people with pheochromocytoma
  • Greater risk during surgery
  • Hiding symptoms of low blood sugar
  • Masked symptoms of overactive thyroid

Summary for Lopressor

Prescription only

Metoprolol tartrate (Lopressor) is a beta blocker used to treat chest pain and high blood pressure in adults. It can also lower the risk of death after a heart attack. You take it by mouth, typically once or twice a day, but your dose depends on your condition. Side effects include dizziness, shortness of breath, and it can make you tired.

Indications for Lopressor

Pros and Cons for Lopressor

Pros

  • Fast-acting — works quickly after you take it
  • First choice treatment after a heart attack
  • Available in different strengths, so your dose can be adjusted easily
  • Possible option for those who are breastfeeding

Cons

Common Side Effects for Lopressor

  • Tiredness (10%)
  • Dizziness (10%)
  • Diarrhea (5%)
  • Rash (5%)
  • Depression (5%)

Warnings for Lopressor

  • Risks of stopping treatment suddenly
  • Worsening heart failure
  • Risk of difficulty breathing
  • Major surgery
  • Hiding symptoms of low blood sugar
  • Hiding symptoms of overactive thyroid
  • Severe allergic reactions

Prices with our coupons for Toprol XL vs. Lopressor

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Metoprolol ER90 tablets / 25mg
$15.75$101.53
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Metoprolol60 tablets / 25mg
$9.00$9.00
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