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Tegretol vs. Topamax

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Carbamazepine (Tegretol) and Topiramate (Topamax) are both antiepileptic medications, but they have different uses and side effects. Carbamazepine is used to treat various types of seizures, trigeminal neuralgia (a type of facial nerve pain), and bipolar I disorder (Equetro brand only). It works by blocking sodium channels in the brain. Topiramate, on the other hand, is used to treat seizures and prevent migraines. It works by blocking certain signals in the brain that can cause seizures. Carbamazepine is available in many forms, including pills, chewable tablets, and liquid, and it can be taken up to four times a day. Topiramate also comes in various forms, including immediate-release and extended-release tablets and capsules, and is typically taken once or twice daily. Common side effects of carbamazepine include dizziness, sleepiness, and stomach upset, while topiramate can cause weight loss, drowsiness, and trouble thinking clearly. Both medications can cause serious side effects, such as suicidal thoughts and severe skin reactions, but topiramate also has risks like kidney stones and high blood acid levels, while carbamazepine can also cause low blood sodium and liver problems. Additionally, both medications can affect the effectiveness of birth control pills.

Carbamazepine

(Tegretol)

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Topiramate

(Topamax)

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Summary for Tegretol

Prescription only

Carbamazepine (Tegretol) is an antiseizure medication used to treat different kinds of seizures. It can also help with trigeminal neuralgia, a type of facial nerve pain. Brand name Equetro is the only formulation that's approved to treat bipolar I disorder. Carbamazepine (Tegretol) available as pills and a liquid. Depending on formulation you take and what medical condition you have, carbamazepine (Tegretol) is taken by mouth 1 to 4 times per day. Common side effects include sleepiness, dizziness, and stomach upset.

Indications for Tegretol

Pros and Cons for Tegretol

Pros

  • Works well for different types of seizures and trigeminal neuralgia (facial nerve pain)
  • Helps stabilize mood in people with bipolar disorder (Equetro brand only)
  • Available as a lower-cost generic
  • Comes in many dosage forms (e.g., chewable tablets, oral pills, liquid form) for people who have difficulty swallowing pills

Cons

  • Might need to take the immediate-release form of the medication up to 4 times a day
  • Can cause a lot of side effects
  • Might require routine blood testing while taking the medication to see how it's affecting your body
  • Can make hormonal birth control not work as well

Common Side Effects for Tegretol

  • Dizziness (44%)
  • Sleepiness (32%)
  • Nausea (29%)
  • Vomiting (18%)
  • Difficulty walking or keeping balance (15%)
  • Constipation (10%)
  • Itching (8%)
  • Dry mouth (8%)
  • Weakness (8%)
  • Rash (7%)
  • Blurry vision (6%)
  • Speech problems (6%)

Warnings for Tegretol

  • Severe skin reactions
  • Low blood cell counts
  • Severe allergic reactions
  • Suicidal thoughts or behavior
  • Harm to unborn babies
  • Withdrawal
  • Difficulty with speech, concentration, and movement
  • Liver problems
  • Low sodium levels
  • High eye pressure
  • Heart block (heart rhythm problems)

Summary for Topamax

Prescription only

Topiramate (Topamax) belongs to the drug class called antiepileptics. It can be used alone or together with other medications to treat certain types of seizures in people 2 years and older. Topiramate (Topamax) can also be used to prevent migraines in people 12 years and older. It comes as immediate-release tablets and sprinkle capsules. The dosage is taken by mouth twice daily. Topiramate (Topamax) has many possible side effects, like weight loss and tingling of the arms and legs. It can also interact with many other medications.

Indications for Topamax

Pros and Cons for Topamax

Pros

  • Can take by itself or with other medications to control seizures
  • An option for preventing migraines
  • Also available as a sprinkle capsule that you can open and mix contents with soft food (for people who have trouble swallowing pills)
  • Approved for both adults and children (age depends on the health problem)

Cons

Common Side Effects for Topamax

  • "Pins and needles" feeling
  • Sleepiness
  • Dizziness
  • Fatigue
  • Low appetite
  • Weight loss
  • Nervousness
  • Depression
  • Trouble concentrating
  • Trouble remembering things
  • Trouble sleeping
  • Trouble moving or keeping balance
  • Fever
  • Mood changes
  • Change in taste

Warnings for Topamax

  • Vision problems
  • High body temperature and trouble sweating
  • Too much acid in the blood (metabolic acidosis)
  • Changes in mood and risk of suicidal thoughts or behavior
  • Problems with memory, speech, or coordination
  • Sleepiness, tiredness, and lower concentration
  • High ammonia levels in the blood
  • Serious skin reactions
  • Kidney stones
  • Risk of seizures if you stop the medication suddenly
  • Bone or growth problems in children
  • Interaction with other medications
  • Harm to an unborn baby

Prices with our coupons for Tegretol vs. Topamax

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Carbamazepine180 tablets / 200mg
$38.31$154.29
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Topiramate30 tablets / 25mg
$4.50$4.50
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