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Tambocor vs. Amiodarone

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Flecainide (generic name: flecainide) and Amiodarone (generic name: amiodarone, brands: Pacerone, Nexterone) are both antiarrhythmic medications used to treat abnormal heart rhythms, but they have some key differences. Flecainide works by blocking sodium channels to slow down the heart's electrical activity, while Amiodarone blocks various receptors and channels in the heart. Flecainide is typically used for paroxysmal supraventricular tachycardias, paroxysmal atrial fibrillation/flutter, and ventricular arrhythmias, whereas Amiodarone is mainly used for preventing and treating recurrent ventricular arrhythmias. Flecainide is available as a generic and is taken orally, while Amiodarone is available both as a generic oral tablet and as an injection. Amiodarone must be started in a hospital due to its serious side effects, which include lung and liver damage, vision problems, and thyroid issues. Flecainide can cause dizziness and changes in vision but is not recommended for those with heart failure or a recent heart attack. Both medications require careful monitoring by a healthcare provider to avoid severe side effects and interactions with other medications.

Flecainide

 

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Amiodarone

(Pacerone)

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Summary for Tambocor

Prescription only

Flecainide is a prescription antiarrhythmic medication used to prevent abnormal heart rhythms, including paroxysmal atrial fibrillation/flutter (PAF), paroxysmal supraventricular tachycardia (PSVT) and ventricular arrhythmias in adults and certain children. It comes as tablets that you take by mouth, typically two times a day, but your exact dose depends on your heart condition. Because it affects your heart rhythm, it requires regular heart monitoring. Common side effects include dizziness, vision changes, and shortness of breath.

Indications for Tambocor

Pros and Cons for Tambocor

Pros

  • Helps control and prevent abnormal heart rhythms
  • Is a tablet taken by mouth
  • Used in both adults and children

Cons

  • Requires careful heart rhythm monitoring
  • Generally for people with severe heart problems
  • Not safe in people who had a recent heart attack

Common Side Effects for Tambocor

  • Dizziness (19%)
  • Vision changes (16%)
  • Shortness of breath (10%)
  • Headache (10%)
  • Nausea (9%)
  • Tiredness (8%)
  • Heart pounding (6%)
  • Chest pain (5%)
  • Weakness (5%)
  • Tremor (5%)
  • Constipation (4%)
  • Swelling in the arms and legs (4%)
  • Stomach pain (3%)

Warnings for Tambocor

  • Greater risk of death after recent heart attack
  • New or worsening heart rhythm problems
  • Heart failure
  • Slowed electrical signals through the heart
  • Fixing electrolyte levels

Summary for Amiodarone

Prescription only

Amiodarone (Pacerone) is an antiarrhythmic medication. It's FDA-approved to treat life-threatening ventricular fibrillation and fast heart rate (tachycardia) in adults who either can't take it or whose condition isn't well-controlled by other antiarrhythmics. It's sometimes prescribed off-label for atrial fibrillation (AFib). Amiodarone (Pacerone) comes as tablets that are taken by mouth. The total daily dose can be taken once per day, or split into smaller doses and taken throughout the day to prevent stomach-related side effects, like nausea and vomiting.

Indications for Amiodarone

  • Life-threatening ventricular fibrillation that keeps coming back (when other antiarrhythmics haven't worked well)
  • Life-threatening tachycardia that keeps coming back (when other antiarrhythmics haven't worked)

Pros and Cons for Amiodarone

Pros

  • Works well to treat certain heart rate and rhythm problems
  • Can be taken with or without food
  • Can be taken once daily (as long as you're tolerating the medication and the total daily dose is less than 1,000 mg)

Cons

  • Stays in the body for many weeks
  • Not for people with iodine allergy
  • Only available as a 200 mg tablet, so you might need to take several tablets depending on your dose

Common Side Effects for Amiodarone

Warnings for Amiodarone

  • Arrhythmia (abnormal heartbeat)
  • Lung damage
  • Liver damage
  • Vision problems
  • Thyroid problems
  • Slow heartbeat
  • Effects on heart devices
  • Harm to unborn babies
  • Nerve problems

Prices with our coupons for Tambocor vs. Amiodarone

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Flecainide60 tablets / 50mg
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Amiodarone90 tablets / 200mg
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