Key takeaways
Montelukast (Singulair) and Symbicort (budesonide/formoterol) are both used to manage asthma, but they work in different ways and have distinct uses. Montelukast is a leukotriene receptor antagonist taken orally, which helps reduce inflammation and swelling by blocking leukotrienes. It's also used for treating year-round and seasonal allergies and preventing exercise-induced asthma. Symbicort, on the other hand, is an inhaler that combines a corticosteroid (budesonide) and a long-acting beta-agonist (formoterol) to reduce lung inflammation and relax airway muscles. Symbicort is used for both asthma and chronic obstructive pulmonary disease (COPD). Montelukast is typically taken once daily, while Symbicort is used twice daily. Montelukast is available in generic form and is suitable for children as young as 1 year old, whereas Symbicort is available in two strengths and is safe for children 6 years and older for asthma. Montelukast can cause serious mental health side effects, while Symbicort may lead to oral thrush and bone loss with long-term use.
