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Singulair vs. Claritin

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Montelukast (Singulair) and loratadine (Claritin) are both used to treat allergies, but they work in different ways and are used for different purposes. Montelukast is a leukotriene receptor antagonist that helps manage asthma and prevent exercise-induced asthma, in addition to treating seasonal and year-round allergies. It is available only by prescription and comes in various forms, including tablets, chewable tablets, and oral granules. Montelukast is not suitable for immediate relief of asthma attacks. Loratadine, on the other hand, is an over-the-counter antihistamine that primarily provides short-term relief for allergy symptoms like runny nose and itchy eyes. It is available in tablets, chewable tablets, and oral solutions. Loratadine is not recommended for children under 2 years old without a healthcare provider's advice. Montelukast is taken once daily, usually in the evening for asthma, while loratadine is also taken once daily but can be taken at any time. Montelukast may cause serious mental health side effects, whereas loratadine heachache and dry mouth. Loratadine is less likely to cause drowsiness compared to other antihistamines but can still make you sleepy.

Montelukast

(Singulair)

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Loratadine

(Claritin)

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Summary for Singulair

Prescription only

Montelukast, the generic for Singulair, is used to help control asthma over time and prevent breathing problems during exercise in both adults and children. It's also used to help relieve allergy symptoms. Montelukast (Singulair) comes as tablets, chewable tablets, or oral granules and is usually taken by mouth once a day. Common side effects include upper respiratory infection and headache, and it has a boxed warning for serious mood and behavior changes.

Indications for Singulair

Pros and Cons for Singulair

Pros

  • Only need to take once a day
  • Helps prevent asthma symptoms and allergies
  • Available in child‑friendly forms (chewable tablets, oral granules)

Cons

  • Not for treating sudden asthma attacks
  • Might cause serious mood or behavior changes
  • Not always a first‑choice option for allergies

Common Side Effects for Singulair

  • Upper respiratory infection
  • Fever
  • Headache
  • Sore throat
  • Cough
  • Stomach pain
  • Diarrhea
  • Earache or ear infection
  • Flu
  • Runny nose
  • Sinus infection

Warnings for Singulair

  • Mood or behavior changes
  • Not for asthma attacks
  • High white blood cell counts
  • Chewable tablets not for people with phenylketonuria (PKU)

Summary for Claritin

Over-the-counter

Loratadine (Claritin) is an over-the-counter antihistamine for adults and kids. It helps relieve allergy symptoms like a runny nose, sneezing, and watery eyes. This allergy medication is taken by mouth, usually once a day. It comes as different formulations, including regular tablets, chewable tablets, and a liquid. Loratadine (Claritin) is a non-drowsy allergy medication because it's less likely to make you sleepy. Other side effects can include headache and feeling tired. Loratadine (Claritin) is available as a brand-name and generic.

Indications for Claritin

  • Short-term relief of allergy symptoms (runny nose, itchy nose or throat, itchy or watery eyes)

Pros and Cons for Claritin

Pros

Cons

  • Can take 1 to 3 hours to start working
  • Regular tablets and quick-dissolving tablets not for children younger than 6
  • Might have a higher risk of side effects if you have liver or kidney problems

Common Side Effects for Claritin

  • Headache (12%)
  • Sleepiness (8%)
  • Feeling tired (4%)
  • Dry mouth (3%)

Warnings for Claritin

  • Sleepiness
  • Accidentally taking too much medication
  • Caution use in people with phenylketonuria (PKU) - chewable tablets and orally disintegrating tablets

Prices with our coupons for Singulair vs. Claritin

Price Card Drug Icon
Montelukast30 tablets / 10mg
$8.73$93.48
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Loratadine30 tablets / 24 hour
$8.59$8.93
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