Key takeaways
Montelukast (Singulair) and Breo Ellipta (fluticasone/vilanterol) are both used to manage asthma, but they work in different ways and have different uses. Montelukast is a leukotriene receptor antagonist, which helps reduce inflammation and swelling by blocking leukotrienes. It is taken orally once daily, usually in the evening. Montelukast also helps manage seasonal and year-round allergies and can prevent exercise-induced asthma. Breo Ellipta, on the other hand, is an inhaled combination of a corticosteroid (fluticasone) and a long-acting beta agonist (vilanterol). It helps by reducing lung inflammation and relaxing lung muscles to open airways. Breo Ellipta is also used for chronic obstructive pulmonary disease (COPD) and is taken once daily through inhalation. Montelukast is available in various forms, including chewable tablets and granules, making it suitable for children. Breo Ellipta requires rinsing your mouth after use to prevent fungal infections, while montelukast does not have this requirement. Both medications are available as lower-cost generics.
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