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Mucinex DM vs. Nyquil

Mucinex DM (guaifenesin / dextromethorphan) is an over-the-counter medication that's used to relieve cough and loosen mucus. It has two active ingredients: guaifenesin (an expectorant that clears chest congestion) and dextromethorphan (a cough suppressant that relieves cough). The medication is available as tablets, dissolvable granules, and liquid that are taken by mouth, each with different dosages, directions, and age limits. Extended-release tablets are taken every 12 hours, while the other forms are usually taken every 4 hours. Most people have few to no side effects when used as directed, but it can sometimes cause stomach upset, dizziness, and drowsiness.

• Short-term relief of coughs caused by minor throat or lung irritation (e.g., common cold)
• Loosens and breaks up mucus in the airways (chest congestion)

• Side effects aren't common. See Other Side Effects.

• Risk of overdose and misuse
• Interactions with certain medications for Parkinson's disease and depression
• Caution use in people with phenylketonuria (PKU) - dissolvable granules only

Nyquil Cold and Flu is a combination medication containing acetaminophen (a pain reliever), dextromethorphan (a cough suppressant), and doxylamine (an antihistamine). It's used to treat cold and flu symptoms, like sore throat, fever, cough, runny nose, sneezing, and aches, in adults and children. Nyquil Cold and Flu is available as pills and a liquid. This medication can make you feel sleepy and dizzy as side effects.

Temporarily relieves common cold and flu symptoms, including:

• Cough
• Sore throat
• Headache
• Minor aches and pains
• Fever
• Runny nose
• Sneezing

• Sleepiness
• Dizziness
• Dry mouth

• Liver damage
• Serotonin syndrome
• Accidental overdose
• Worsening of medical conditions
• Allergic skin reactions