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Compare Rhinocort Allergy vs. Nyquil

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Rhinocort Allergy (budesonide) and Nyquil Cold and Flu (acetaminophen/dextromethorphan/doxylamine) are both used to treat symptoms related to respiratory issues, but they work differently and are used for different conditions. Rhinocort Allergy is a corticosteroid nasal spray that helps reduce inflammation in your nose to treat allergy symptoms like sneezing, runny nose, and itching. It is available over-the-counter and as a lower-cost generic. You use it once daily, and it can take up to two weeks to feel the full benefit. On the other hand, Nyquil Cold and Flu is a combination of a pain reliever, cough suppressant, and antihistamine, used to relieve cold and flu symptoms such as cough, sore throat, fever, and runny nose. It works quickly, within 30 minutes, but may need to be taken multiple times a day. Nyquil can make you very sleepy and should not be used long-term. Unlike Rhinocort, Nyquil is available in both liquid and capsule forms. While Rhinocort is focused on treating allergies, Nyquil addresses a broader range of cold and flu symptoms.

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