Key takeaways
Risperidone (Risperdal) and Aristada (aripiprazole lauroxil) are both atypical antipsychotics used to treat schizophrenia, but they have some key differences. Risperidone is available in oral forms, including tablets, dissolvable tablets, and liquid, and can also treat bipolar disorder and irritability associated with autism. In contrast, Aristada is a long-acting injection given every 1 to 2 months and is only used for schizophrenia. Risperidone can be used in both adults and children, while Aristada is only for adults. Risperidone is available as a lower-cost generic, whereas Aristada is only available as a brand medication and can be expensive. Common side effects of risperidone include sleepiness and weight gain, while Aristada can cause restlessness and injection site pain. Both medications can cause serious side effects like neuroleptic malignant syndrome and tardive dyskinesia, but Aristada also has a risk of impulsive behaviors.
