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Pantoprazole vs. Mylanta Maximum Strength

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Pantoprazole (Protonix) and Mylanta Maximum Strength (aluminum hydroxide/magnesium hydroxide/simethicone) are both used to treat stomach issues, but they work differently and are used for different purposes. Pantoprazole (Protonix) is a prescription-only proton pump inhibitor (PPI) that reduces stomach acid production and is used for conditions like GERD and erosive esophagitis. It is taken once daily and can be administered orally or via intravenous injection. Common side effects include headache and diarrhea. On the other hand, Mylanta Maximum Strength is an over-the-counter medication that combines two antacids and a gas relief agent to quickly neutralize stomach acid and relieve symptoms like heartburn, sour stomach, and gas. It is taken as needed, multiple times a day, and common side effects include diarrhea and nausea. Unlike pantoprazole, Mylanta Maximum Strength is not recommended for long-term use, and may not be suitable for people with kidney problems or those on a magnesium-restricted diet. Although it sometimes is used long-term, pantoprazole's long-term use may lead to more serious side effects like bone fractures and kidney problems.

Pantoprazole

(Protonix)

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Mylanta Maximum Strength

 

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Summary for Pantoprazole

Prescription only

Pantoprazole (Protonix) is a proton-pump inhibitor (PPI). It's used to treat symptoms of gastroesophageal reflux disease (GERD) in adults and children. It's also used to treat other conditions involving too much stomach acid, such as erosive esophagitis, in adults only. Pantoprazole (Protonix) is taken by mouth, typically once daily for most conditions. Some of the more common side effects of this medication include headache and diarrhea. Pantoprazole (Protonix) isn't available over-the-counter (OTC).

Indications for Pantoprazole

Pros and Cons for Pantoprazole

Pros

  • Can continue to use with antacids, such as calcium carbonate
  • Available as a lower-cost generic medication
  • Oral tablets can be taken without regard to food
  • Available in oral granules and suspension for people with trouble swallowing

Cons

  • Long-term use might weaken bones and raise the risk of bone fractures
  • Might cause or worsen lupus
  • Interacts with warfarin (Coumadin), which can raise the risk of bleeding
  • Not available over-the-counter

Common Side Effects for Pantoprazole

  • Headache (12%)
  • Diarrhea (9%)
  • Nausea (7%)
  • Belly pain (6%)

Please note: Side effect percentages are listed for adults with GERD.

Warnings for Pantoprazole

  • Risk of hiding symptoms of a more serious problem
  • Sudden kidney problems
  • Severe infectious diarrhea
  • Bone fractures
  • Skin reactions
  • Lupus
  • Low vitamin B12 and magnesium levels
  • Interaction with other medications
  • Inaccurate lab work

Summary for Mylanta Maximum Strength

Over-the-counter

Mylanta Maximum Strength is a combination medication containing three active ingredients: two antacids (aluminum hydroxide and magnesium hydroxide) and a gas medication (simethicone). It's used to help relieve the symptoms of heartburn, acid reflux, and gas. This medication is available over the counter (OTC) as a liquid for people ages 12 years and older. The dosage is 10 to 20 mL taken by mouth in between meals and at bedtime as needed. Possible side effects include diarrhea and nausea.

Indications for Mylanta Maximum Strength

Short-term relief of:

  • Heartburn
  • Sour stomach
  • Indigestion
  • Gas (bloating, pressure, discomfort)

Pros and Cons for Mylanta Maximum Strength

Pros

  • Provides fast relief (within several minutes)
  • Can take multiples times throughout the day for continued symptom relief
  • Comes as a flavored suspension
  • Available as a lower-cost generic medication
  • Can be purchased over the counter (OTC), without a prescription

Cons

  • Doesn't last as long as other types of heartburn medications
  • Can interfere with how well other medications are absorbed into the body
  • Might not be a good option for people with kidney problems or on a magnesium-restricted diet
  • Not recommended for use during pregnancy
  • Contains magnesium, so can cause diarrhea

Common Side Effects for Mylanta Maximum Strength

Warnings for Mylanta Maximum Strength

  • Toxicity from too much magnesium
  • Toxicity from too much aluminum

Prices with our coupons for Pantoprazole vs. Mylanta Maximum Strength

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Pantoprazole30 tablets / 40mg
$9.87$16.47
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Price Card Drug Icon
Aluminum Hydroxide/Magnesium Hydroxide/Simethicone1 bottle / 355ml of 400mg/400mg/40mg/10ml
$12.43-
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