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Compare Tagamet HB vs. Mylanta Maximum Strength

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Cimetidine (Tagamet HB) and Mylanta Maximum Strength (aluminum hydroxide/magnesium hydroxide/simethicone) are both used to treat heartburn and related stomach issues. However, they belong to different medication classes. Cimetidine is a histamine H2 receptor antagonist (H2RA) that reduces stomach acid production, while Mylanta Maximum Strength is a combination of antacids and an antiflatulent that neutralizes stomach acid and relieves gas. Both medications are available over-the-counter and come as an oral liquid, but cimetidine also comes as an oral tablet. Cimetidine can be used for conditions like GERD and ulcers, while Mylanta Maximum Strength is for short-term relief of heartburn, sour stomach, indigestion, and gas. Cimetidine may cause side effects like headache and dizziness and has many drug interactions. Mylanta Maximum Strength can cause diarrhea and nausea and may not be suitable for people with kidney problems. Cimetidine may sometimes be used off-label for molluscum contagiosum.

  • Cimetidine (Tagamet HB)
    Mylanta maximum strength
  • Cimetidine (Tagamet HB)
    Mylanta maximum strength

  • Summary of Tagamet HB vs. Mylanta Maximum Strength

    Summary for Histamine H2 receptor antagonist (H2RA)

    Cimetidine (Tagamet HB) is a histamine H2 receptor antagonist (H2RA) that lowers how much acid is made in the stomach. The over-the-counter (OTC) version relieves and prevents heartburn in people 12 years and older. Higher strengths of cimetidine are prescription only and are used to treat acid reflux, stomach and gut ulcers, and other stomach acid problems in people 16 years and older. Cimetidine (Tagamet HB) is taken by mouth one to four times a day, depending on what stomach problem you have. This medication has few side effects, which can include headache, dizziness, and diarrhea.

    Summary for Antacid / Antiflatulent

    Mylanta Maximum Strength is a combination medication containing three active ingredients: two antacids (aluminum hydroxide and magnesium hydroxide) and a gas medication (simethicone). It's used to help relieve the symptoms of heartburn, acid reflux, and gas. This medication is available over the counter (OTC) as a liquid for people ages 12 years and older. The dosage is 10 to 20 mL taken by mouth in between meals and at bedtime as needed. Possible side effects include diarrhea and nausea.

  • Indications of Tagamet HB vs. Mylanta Maximum Strength

    Indications for
    •Heartburn related to indigestion and sour stomach - OTC only
    •Erosive gastroesophageal reflux disease (GERD) - prescription only
    •Gastric and duodenal ulcers - prescription only
    •Conditions that cause too much stomach acid (such as Zollinger-Ellison syndrome) - prescription only
    Indications for

    Short-term relief of:

    •Heartburn
    •Sour stomach
    •Indigestion
    •Gas (bloating, pressure, discomfort)

  • Pros and Cons of Tagamet HB vs. Mylanta Maximum Strength

    Pros and Const for Histamine H2 receptor antagonist (H2RA)
    Pros
    •Available as an OTC product for heartburn only
    •Available as a tablets and an oral solution
    Cons
    •Interacts with many medications, including warfarin (Coumadin) and propranolol
    •Might not work as well as you continue taking the medication (when taken long-term)
    Pros and Const for Antacid / Antiflatulent
    Pros
    •Provides fast relief (within several minutes)
    •Can take multiples times throughout the day for continued symptom relief
    •Comes as a flavored suspension
    •Available as a lower-cost generic medication
    •Can be purchased over the counter (OTC), without a prescription
    Cons
    •Doesn't last as long as other types of heartburn medications
    •Can interfere with how well other medications are absorbed into the body
    •Might not be a good option for people with kidney problems or on a magnesium-restricted diet
    •Not recommended for use during pregnancy
    •Contains magnesium, so can cause diarrhea

  • Common Side Effects of Tagamet HB vs. Mylanta Maximum Strength

    Common Side Effects for
    •Diarrhea
    •Headache
    •Dizziness
    •Sleepiness
    Common Side Effects for
    •Diarrhea
    •Nausea
    •Constipation

  • Warnings of Tagamet HB vs. Mylanta Maximum Strength

    Common Side Effects for
    •Speak with provider if symptoms don't go away or come back
    •Confusion
    •Drug interactions
    Common Side Effects for
    •Toxicity from too much magnesium
    •Toxicity from too much aluminum

  • Prices with our coupons for Tagamet HB vs. Mylanta Maximum Strength

    Learn more about Cimetidine
    Learn more about Mylanta maximum strength

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