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Movantik vs. Miralax

Movantik (naloxegol) is an opioid antagonist that's used to treat opioid-induced constipation, or constipation from opioid medications, in adults. It's a tablet that's taken by mouth once every morning on an empty stomach. The dosage is typically 25 mg, but it can be lowered to lessen side effects or risks from interactions with other medications. Common side effects include stomach pain, diarrhea, and nausea. Movantik (naloxegol) is available as a brand-name medication only; there's no lower-cost generic version yet.

• Constipation from opioid pain medications in adults

• Stomach pain (up to 21%)
• Diarrhea (up to 9%)
• Nausea (up to 8%)

• Opioid withdrawal
• Severe stomach pain or diarrhea
• Gastrointestinal (stomach or intestinal) injury
• Allergic reaction

Polyethylene glycol (Miralax) is an over-the-counter (OTC) medication used for occasional constipation. It comes as a powder that you need to mix with a beverage and then drink. Typically, you take a dose of polyethylene glycol (Miralax) once a day, for up to a week. Most people will experience a bowl movement in 1 to 3 days. Some side effects that polyethylene glycol (Miralax) can cause include nausea, bloating, and passing gas.

• Occasional constipation and irregular bowel movements

• Nausea
• Passing gas
• Bloating

• Complete or partial blockage of intestines