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Movantik vs. Magnesium citrate

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Movantik (naloxegol) and magnesium citrate (Citroma) are both used to treat constipation, but they work in different ways and are used for different types of constipation. Movantik is a prescription medication specifically for constipation caused by opioid pain medications. It works by blocking opioid receptors in the intestines, helping you have a bowel movement. You take it once daily on an empty stomach. Common side effects include stomach pain, diarrhea, and nausea. Movantik is only available as a brand-name medication. On the other hand, magnesium citrate is an over-the-counter saline laxative used for occasional constipation. It helps your intestines hold onto water, making it easier to have a bowel movement. It usually works within 30 minutes to 6 hours. Magnesium citrate comes in liquid form and is available in different flavors. It’s important to avoid it if you have kidney problems or electrolyte imbalances. Common side effects include nausea, stomach pain, and diarrhea. Unlike Movantik, magnesium citrate has many generic options available.

Movantik

(naloxegol)

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magnesium citrate

 

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Summary for Movantik

Prescription only

Movantik (naloxegol) is an opioid antagonist that's used to treat opioid-induced constipation, or constipation from opioid medications, in adults. It's a tablet that's taken by mouth once every morning on an empty stomach. The dosage is typically 25 mg, but it can be lowered to lessen side effects or risks from interactions with other medications. Common side effects include stomach pain, diarrhea, and nausea. Movantik (naloxegol) is available as a brand-name medication only; there's no lower-cost generic version yet.

Indications for Movantik

Pros and Cons for Movantik

Pros

  • A good option to help with constipation from opioids
  • Taken by mouth once a day
  • Tablets can be crushed and mixed with water for people who have trouble swallowing them whole

Cons

  • Must take on an empty stomach
  • Might have opioid withdrawal symptoms
  • Might not work as well if you've been taking opioids for less than 1 month

Common Side Effects for Movantik

  • Stomach pain (up to 21%)
  • Diarrhea (up to 9%)
  • Nausea (up to 8%)

Warnings for Movantik

  • Opioid withdrawal
  • Severe stomach pain or diarrhea
  • Gastrointestinal (stomach or intestinal) injury
  • Allergic reaction

Summary for Magnesium citrate

Over-the-counter

Magnesium citrate is a oral laxative solution that can ease the occasional constipation. It's available over the counter (OTC) and can help produce a bowel movement in 30 minutes to 6 hours. Magnesium citrate might not be a safe option if you have kidney problems or electrolyte levels that are out of balance.

Indications for Magnesium citrate

  • Occasional constipation

Pros and Cons for Magnesium citrate

Pros

  • Works fast, produces a bowel movement within 30 minutes to 6 hours
  • Available OTC without a prescription
  • Comes in different flavors
  • Many generic products available

Cons

  • Only for use with occasional constipation
  • Might not be a good option for people with kidney problems or those who need to limit magnesium or sodium intake
  • Can cause nausea and vomiting
  • Needs to be separated from other medications

Common Side Effects for Magnesium citrate

Warnings for Magnesium citrate

  • Complete or partial blockage of intestines
  • Kidney and other health conditions

Prices with our coupons for Movantik vs. Magnesium citrate

Price Card Drug Icon
Movantik30 tablets / 25mg
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Magnesium Citrate1 bottle / 296ml
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