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Lexapro vs. Xanax

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Escitalopram (Lexapro) and alprazolam (Xanax) are both medications used to treat generalized anxiety disorder (GAD), but they belong to different medication classes. Escitalopram is a selective serotonin reuptake inhibitor (SSRI) that is also approved for treating depression, while alprazolam is a benzodiazepine used for GAD and panic disorder. Escitalopram is typically taken once a day, whereas alprazolam is usually taken up to three times a day. Escitalopram is available in both brand and generic forms, as is alprazolam. Alprazolam is also available in an extended-release form (Xanax XR). Common side effects of escitalopram include nausea and trouble sleeping, while alprazolam can cause drowsiness and memory problems. Both can interact with many medications and have a risk of withdrawal symptoms if stopped suddenly. Alprazolam is a controlled substance due to its potential for misuse and dependence, while escitalopram is not.

Escitalopram

(Lexapro)

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Alprazolam

(Xanax)

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Summary for Lexapro

Prescription only

Escitalopram, also known by its brand name, Lexapro, is a selective serotonin reuptake inhibitor (SSRI). It's a first-choice antidepressant to treat depression and anxiety in adults and children. The medication is available as a tablet and oral solution, in both brand and generic forms. A dose is typically taken by mouth once per day. Some common side effects include nausea, trouble sleeping (insomnia), and dizziness.

Indications for Lexapro

Pros and Cons for Lexapro

Pros

  • First-choice medication for anxiety and depression
  • Only need to take it once a day
  • Generally has fewer side effects compared to other antidepressants
  • Can be taken with or without food

Cons

  • Can take up to 2 months before you feel the the full benefits
  • Risk of certain sexual problems
  • Can raise your risk for bleeds
  • Can cause withdrawal symptoms if you suddenly stop taking it

Common Side Effects for Lexapro

  • Headache (24%)
  • Nausea (15-18%)
  • Ejaculation problems (9-14%)
  • Sleepiness (6-13%)
  • Trouble sleeping (9-12%)
  • Dry mouth (6-9%)
  • Diarrhea (8%)
  • Tiredness (5-8%)

Warnings for Lexapro

  • Worsening depression, suicidal thoughts, and unusual behavior
  • Serotonin syndrome
  • Stopping escitalopram (Lexapro) too suddenly
  • Risk of bleeding
  • Not for use alone in bipolar disorder
  • Glaucoma
  • Life-threatening abnormal heart rhythm (QT prolongation)
  • Low blood sodium levels
  • Sexual problems

Summary for Xanax

Prescription only

Alprazolam (Xanax) is a benzodiazepine. It's approved to treat generalized anxiety disorder (GAD) and panic attacks in adults. It's taken by mouth, typically 3 times a day or as directed by your healthcare team. To avoid the risk of dependence, alprazolam (Xanax) is meant for short-term treatment only. Some of the more common side effects of this medication include drowsiness and memory problems. You should avoid drinking alcohol while taking alprazolam (Xanax) because this can lead to serious interactions.

Indications for Xanax

Pros and Cons for Xanax

Pros

  • Taken by mouth
  • Can start to work in 30 minutes
  • Available as quick-dissolving tablets or liquid for people who have trouble swallowing pills

Cons

Common Side Effects for Xanax

Generalized anxiety disorder:

  • Drowsiness (41%)
  • Lightheadedness (21%)
  • Dry mouth (15%)

Panic disorder:

  • Drowsiness (77%)
  • Fatigue (49%)
  • Poor coordination (40%)
  • Memory issues (33%)
  • Irritability (33%)
  • Appetite changes (28-33%)
  • Thinking problems (29%)
  • Constipation (26%)

Side effects listed are for the immediate-release forms. Side effects for extended-release form might differ.

Warnings for Xanax

  • Sedation and difficulty breathing
  • Potential for misuse, addiction, dependence, and withdrawal
  • Effect on driving and concentration
  • Harm to babies
  • Interactions with other medications
  • Use with caution in people with depression

Prices with our coupons for Lexapro vs. Xanax

Price Card Drug Icon
Escitalopram30 tablets / 10mg
$9.51$17.33
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Alprazolam30 tablets / 0.5mg
$10.40$14.84
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