Key takeaways
Levofloxacin (generic only, brand name Levaquin no longer available) and moxifloxacin (generic only, brand name Avelox no longer available) are both fluoroquinolone antibiotics used to treat serious bacterial infections. While both medications can treat lung, skin, and sinus infections, levofloxacin is also used for urinary tract infections, kidney infections, and long-term prostate infections, which moxifloxacin is not typically prescribed for. Levofloxacin is available in multiple forms, including tablets, oral liquid, and injection, whereas moxifloxacin is only available in tablet and infection forms. Both medications have serious side effects, such as tendon rupture and nerve damage, as well as additional warnings for changes in blood sugar levels, which is particularly important for people with diabetes. Additionally, moxifloxacin should be taken at least 4 hours before or 8 hours after antacids, while levofloxacin should be taken 2 hours before or after such supplements. Both antibiotics can make your skin more sensitive to the sun, so you should take precautions to protect your skin when outside.
