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Compare Humulin R vs. Novolin R

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Humulin R (insulin regular) and Novolin R (insulin regular) are both short-acting insulins used to manage blood sugar levels in people with type 1 and type 2 diabetes. They start working in about 30 minutes and last for several hours. Both medications are available over the counter and can be used with other diabetes medications like metformin. However, Humulin R has a unique, more concentrated form called Humulin R U-500, which is available by prescription only and is meant for those who need large doses of insulin. Novolin R is not available as a concentrated version. Both insulins come in pens and vials, but their storage instructions differ slightly. For example, opened Novolin R vials can be stored at room temperature for up to 42 days, while Humulin R vials can be stored for 31 days. Both medications require careful monitoring of blood sugar levels and proper injection techniques to avoid complications like low blood sugar and infections.

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