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Precose vs. Humalog

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Acarbose (Precose) and Humalog (insulin lispro) are both used to manage diabetes, but they work in different ways and are used for different types of diabetes. Acarbose, available only as a generic, is an alpha-glucosidase inhibitor taken orally to help control blood sugar in adults with Type 2 diabetes. Acarbose needs to be taken multiple times a day with your meal. It works by slowing down the digestion of carbohydrates (form of sugar) in your gut, which helps lower blood sugar levels after meals. Acarbose can cause side effects like gas and diarrhea. On the other hand, Humalog is a fast-acting insulin used for both Type 1 and Type 2 diabetes and is administered by injection. It helps lower blood sugar by moving sugar from your blood into your body’s cells. Humalog should be taken before a meal and starts working within 15 minutes and lasts for 2 to 4 hours. You should not take Humalog if you are planning to skip a meal unless your healthcare provider specifically tells you to, as this increases the risk for low blood sugar. Humalog can cause low blood sugar and weight gain, whereas acarbose is less likely to cause low blood sugar when used alone and might even lead to weight loss.

Acarbose

 

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Humalog

(insulin lispro)

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Summary for Precose

Prescription only

Acarbose is a medication that's used together with a healthy diet and exercise to help control blood sugar in adults with Type 2 diabetes. It isn't as commonly used as other diabetes medications since it can lead to some unpleasant side effects like gas and diarrhea. But acarbose is less likely to cause hypoglycemia compared to other diabetes medications when used on its own. This medication is only available as the generic name acarbose since the brand name Precose has been discontinued.

Indications for Precose

  • Type 2 diabetes

Pros and Cons for Precose

Pros

  • Not likely to cause weight gain, instead it might cause weight loss
  • Helps control blood sugar levels after you're eating
  • Low risk of low blood sugar when used alone
  • Can be used with other diabetes medications
  • Available as a lower-cost generic

Cons

  • Must be taken multiple times a day
  • Needs to be taken with meals
  • Side effects include excessive gas and diarrhea
  • Not recommended for people with severe kidney problems
  • Typically not considered a first-choice treatment option

Common Side Effects for Precose

  • Excessive gas (74%)
  • Diarrhea (31%)
  • Stomach pain (19%)

Warnings for Precose

  • Low blood sugar when taken together with other diabetes medications
  • Changes in liver labs
  • Losing control of blood sugar

Summary for Humalog

Prescription only

Humalog (insulin lispro) is a fast-acting insulin for adults and children with diabetes. It helps prevent and treat high blood sugar from meals. This medication lowers your blood sugar levels by moving the sugar from your blood and into your body. Humalog (insulin lispro) is typically given as an injection under the skin. In certain situations, it's injected into the veins by a healthcare provider. Humalog (insulin lispro) is available as vials and ready-to-use prefilled pens. Side effects include headache and low blood sugar (hypoglycemia).

Indications for Humalog

Pros and Cons for Humalog

Pros

  • Starts to work within 15 minutes to lower blood sugar levels
  • Dose can be easily adjusted to make a treatment plan that's tailored to your specific needs
  • Available as a prefilled pen for easier and convenient use
  • Can use at home after proper training
  • Can use in children as young as 3 years old with Type 1 diabetes

Cons

  • Given multiple times a day (before each meal)
  • Must give as an injection
  • Might be hard for some people to take properly
  • Risk of low blood sugar
  • Can cause weight gain

Common Side Effects for Humalog

Type 1 diabetes:

  • Flu-like symptoms (35%)
  • Sore throat (33%)
  • Runny nose (25%)
  • Headache (30%)
  • Pain (20%)
  • Cough (17%)
  • Infection (14%)

Type 2 diabetes:

  • Headache (12%)
  • Pain (11%)
  • Infection (10%)

Warnings for Humalog

  • Spread of infections from sharing injection supplies
  • Low blood sugar (hypoglycemia)
  • Low blood potassium levels
  • Swelling from fluid buildup and risk of heart failure when taken with certain blood sugar medications
  • Dangerously high blood sugar levels or buildup of ketones (for people who use insulin pump)

Prices with our coupons for Precose vs. Humalog

Price Card Drug Icon
Acarbose90 tablets / 25mg
$23.68$70.07
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Insulin Lispro1 vial / 10ml of 100 units/ml
$33.00$140.15
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