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Gentamicin vs. Neosporin

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Gentamicin

 

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Neosporin

 

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Summary for Gentamicin

Prescription only

Gentamicin is a topical antibiotic that treats bacterial skin infections, such as impetigo. It comes as a cream that's useful for wet, oozing, or greasy skin infections. There's also a topical ointment for infections on dry skin. Both forms are applied on the skin 3 to 4 times a day. Gentamicin can be used on adults and children over 1 year of age. Most people don't have many side effects when used as directed. But it's possible to have mild skin irritation, like redness and itching.

Indications for Gentamicin

  • Impetigo
  • Other bacterial skin infections

Pros and Cons for Gentamicin

Pros

  • Treats various bacterial skin infections, including severe acne or impetigo
  • Very few side effects, so it's safe for most people if used as directed
  • Might be a good option for people who are sensitive to Neosporin

Cons

  • Applied many times a day
  • Can cause temporary skin irritation
  • Need a prescription from a healthcare professional

Common Side Effects for Gentamicin

  • Side effects aren't common. See "Other Side Effects."

Warnings for Gentamicin

  • Risk of other skin infections
  • Allergic reaction

Summary for Neosporin

Over-the-counter

Neosporin, sometimes known as "triple antibiotic," is a combination antibiotic ointment that contains three active ingredients: bacitracin, polymyxin B, and neomycin. Neosporin is used to help prevent skin infections in minor cuts, scrapes, and burns, as these wounds heal. But it's not meant to treat animal bites, serious burns, or deep puncture wounds - those might require medical attention. It's available over the counter and as a lower-cost generic medication.

Indications for Neosporin

  • Preventing infections in minor cuts, scrapes, and burns

Pros and Cons for Neosporin

Pros

  • Combines three antibiotics into one ointment for convenience
  • Available over the counter
  • Works well to prevent infections in minor cuts, scrapes, and burns
  • Comes in different sizes
  • Available as a lower-cost generic medication

Cons

  • Might need to use it a few times per day
  • Can be messy to use
  • Not meant for long-term use
  • Can't be used to treat infections
  • Not for use in your eyes, nose, mouth, ears, or genitals

Common Side Effects for Neosporin

See Risks and Warnings

Warnings for Neosporin

  • Allergic reaction
  • Use only on your skin

Prices with our coupons for Gentamicin vs. Neosporin

Price Card Drug Icon
Gentamicin2 tubes / 15g of 0.1%
$31.50$99.97
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Price Card Drug Icon
Neomycin/Polymyxin B/Bacitracin Non-Prescription1 tube / 28g of 3.5mg/5000iu/400iu
$10.38-
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