Key takeaways
Fluphenazine (generic, formerly known as Prolixin) and Thiothixene (generic, formerly known as Navane) are both typical antipsychotics, but they have some differences. Fluphenazine is used to treat psychotic disorders and is available in both short-acting and long-acting forms, which can be taken orally or via injection. Thiothixene, on the other hand, is used specifically for schizophrenia and is only available in oral form. Fluphenazine is typically taken multiple times a day, while Thiothixene's dosing can vary based on the severity of symptoms, sometimes requiring multiple doses per day as well. Both medications can cause movement problems, including uncontrolled muscle movements. Additionally, Thiothixene is less likely to cause anticholinergic side effects like dry mouth and constipation compared to some other antipsychotics. Both medications should be used with caution in older adults with dementia-related psychosis due to an increased risk of death.
