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Compare Epclusa vs. Technivie

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Epclusa (sofosbuvir/velpatasvir) and Technivie (ombitasvir/paritaprevir/ritonavir) are both antiviral medications used to treat hepatitis C, but they have some key differences. Epclusa is a combination of two antiviral medications and is FDA-approved to treat all six types of chronic hepatitis C in both adults and children. It is taken as one tablet once a day, with or without food. Technivie, on the other hand, was specifically used for type 4 hepatitis C and required combination with ribavirin. It was taken as two tablets in the morning with a meal. Technivie has been discontinued and is no longer available, while Epclusa remains in use. Epclusa can cause mild side effects like headache and fatigue, and it interacts with many medications, including those for heartburn. Technivie was discontinued due to newer medications like Epclusa that do not require ribavirin, which can have many side effects.

  • Epclusa (sofosbuvir / velpatasvir)
    Technivie
  • Epclusa (sofosbuvir / velpatasvir)
    Technivie

  • Summary of Epclusa vs. Technivie

    Summary for Antiviral
    Prescription only

    Epclusa (sofosbuvir / velpatasvir) is a combination medication containing two antiviral medications, sofosbuvir and velpatasvir, that's used to treat chronic hepatitis C in adults and children.

    Summary for Antiviral Combo

    Technivie is a once daily antiviral combination medication once used with ribavirin for the treatment of type 4 hepatitis C. It is no longer available and has been replaced by newer antiviral combination medications.

  • Indications of Epclusa vs. Technivie

    Indications for
    •Chronic hepatitis C infection
    Indications for

  • Pros and Cons of Epclusa vs. Technivie

    Pros and Const for Antiviral
    Pros
    •Treats all 6 types of hepatitis C
    •Most people only have to take one pill once a day for 12 weeks
    •Can be taken with or without food
    •Most common side effects are usually mild, such as fatigue and headache
    Cons
    •Interacts with many medications including those used for heartburn
    •Not a good option for people taking amiodarone (Pacerone) because the combination can cause slow heart rate
    •Some people with severe liver problems who have chronic hepatitis C may need to take it with another antiviral medication called ribavirin
    •Can reactivate the hepatitis B virus if you have a history of hepatitis B infection
    Pros and Const for Antiviral Combo
    Pros
    Cons

  • Common Side Effects of Epclusa vs. Technivie

    Common Side Effects for
    •Headache
    •Fatigue
    Common Side Effects for

  • Warnings of Epclusa vs. Technivie

    Common Side Effects for
    •Hepatitis B reactivation
    •Slow heart rate
    •Ribavirin risks
    •Interactions with other medications
    Common Side Effects for

  • Prices with our coupons for Epclusa vs. Technivie

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    Learn more about Technivie

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