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Bisoprolol vs. Lisinopril

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Bisoprolol (bisoprolol fumarate) and lisinopril (Zestril) are both medications used to treat high blood pressure, but they have some distinct differences. Bisoprolol is a beta blocker that works by slowing down the heart rate, allowing the heart to relax between beats. It's typically used when first-choice blood pressure medications are not effective. Common side effects include headache, fatigue, and dizziness. Lisinopril, on the other hand, is an angiotensin-converting enzyme (ACE) inhibitor that relaxes blood vessels by blocking a protein that tightens them. It's a first-choice medication for high blood pressure and is also used to treat heart failure and reduce the risk of death after a heart attack. Lisinopril can cause a dry cough, dizziness, and headache. Unlike bisoprolol, lisinopril should not be used during pregnancy due to the risk of severe harm to the unborn baby. Both medications are available in generic forms, making them more affordable options.

Bisoprolol

 

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Lisinopril

(Zestril)

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Summary for Bisoprolol

Prescription only

Bisoprolol, or bisoprolol fumarate, is a tablet that's used to treat high blood pressure. It belongs to a group of medications called beta blockers. It's usually only given when first-choice blood pressure medications aren't working well enough. Some common side effects of bisoprolol include headache, feeling tired, and diarrhea. It has some interactions with alcohol and taking bisoprolol with alcohol can worsen dizziness and raise the risk for fainting.

Indications for Bisoprolol

  • High blood pressure

Pros and Cons for Bisoprolol

Pros

  • Works well to lower blood pressure
  • Available as a lower-cost generic
  • Only need to take it once a day
  • Can take it with or without food

Cons

  • Not a first-choice medication to lower blood pressure
  • Skipping or missing doses can lead to high blood pressure and higher risk of heart attacks
  • Can make you feel more tired
  • Can hide symptoms of low blood sugar if you have diabetes

Common Side Effects for Bisoprolol

  • Headache (9%)
  • Fatigue (7%)
  • Upper respiratory tract infection (5%)
  • Swelling in arms or legs (4%)
  • Dizziness (3%)
  • Runny nose (3%)

Warnings for Bisoprolol

  • Heart attack or irregular heart rhythm
  • Heart failure
  • Trouble breathing (people with bronchospastic conditions)
  • Hiding symptoms of low blood sugar
  • Hiding symptoms of high thyroid hormone
  • Severe allergic reactions
  • Worsening of poor circulation

Summary for Lisinopril

Prescription only

Lisinopril (Zestril) is an angiotensin-converting enzyme inhibitor, or ACE inhibitor. It's used to treat high blood pressure in people 6 years and older. In adults, it's also approved to manage heart failure and to lower the risk of death after a heart attack. Lisinopril (Zestril) comes as a tablet that's taken by mouth once daily. There's also an oral solution available under the brand name Qbrelis. Some side effects include dizziness, cough, and headache.

Indications for Lisinopril

Pros and Cons for Lisinopril

Pros

  • Taken by mouth once per day
  • A first-choice medication for high blood pressure
  • Also helpful for heart failure and after a heart attack
  • Okay for children as young as 6 years old to take to treat high blood pressure

Cons

Common Side Effects for Lisinopril

  • Dizziness (up to 19%)
  • Low blood pressure (up to 11%)
  • Higher creatinine levels (up to 10%)

Warnings for Lisinopril

  • Harm to an unborn baby
  • Angioedema (swelling)
  • Low blood pressure
  • Possible worsening of kidney problems
  • High potassium levels
  • Liver problems

Prices with our coupons for Bisoprolol vs. Lisinopril

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Bisoprolol30 tablets / 5mg
$9.00$9.00
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Lisinopril30 tablets / 20mg
$7.79$13.70
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