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Histamine-2 Antagonists

Histamine-2 antagonists are used to treat heartburn, duodenal ulcers, gastric ulcers, and GERD. They work by reducing acid in the stomach to treat symptoms by blocking histamine.

Why are histamine 2 antagonists prescribed?

  1. Heartburn (25%)
  2. Gastric Ulcer (25%)
  3. Duodenal Ulcer (25%)
  4. GERD (25%)

Key takeaways

Histamine-2 antagonists (also called H2 blockers) are used to relieve heartburn and treat conditions like gastroesophageal reflux disease (GERD) and peptic ulcers. They work by blocking histamine-2 receptors in your stomach, which reduces the amount of acid your stomach produces. Histamine-2 antagonists come in different forms, including oral pills and solutions. Examples include famotidine (Pepcid AC, Zantac 360) and cimetidine (Tagamet HB). You can choose the form that best fits your needs.

Prices for popular Histamine-2 Antagonists medications
Viewing 6 of 6 medications
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Pepcid (famotidine)

as low as$8
Famotidine (Pepcid) is a type of antihistamine that blocks the release of stomach acid. It is used to treat stomach or intestinal ulcers. It can also relieve heartburn from acid reflux. It is more popular than comparable drugs. It is available in generic and brand versions.Generic famotidine is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.
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Pepcid AC (famotidine AC)

as low as$8
FAMOTIDINE treats heartburn, stomach ulcers, reflux disease, or other conditions that cause too much stomach acid. It works by reducing the amount of acid in the stomach.
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Tagamet HB (cimetidine HB)

as low as$14
Tagamet HB is only available as a brand name drug.
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cimetidine

as low as$30
CIMETIDINE treats heartburn, stomach ulcers, reflux disease, or other conditions that cause too much stomach acid. It works by reducing the amount of acid in the stomach.
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Axid (nizatidine)

as low as$46
NIZATIDINE is a type of antihistamine that blocks the release of stomach acid. It is used to treat stomach or intestinal ulcers. It can relieve ulcer pain and discomfort, and the heartburn from acid reflux.\n \nThis medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
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Zantac 360

FAMOTIDINE treats heartburn, stomach ulcers, reflux disease, or other conditions that cause too much stomach acid. It works by reducing the amount of acid in the stomach.
See pricesMore info
Disclaimer: Popularity is based on total prescriptions for the brand and generic versions of each drug, regardless of the condition being treated. Some drugs are prescribed for multiple conditions.

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