Beta-blocker-thiazide-like-diuretic combinations are used to treat high blood pressure. These medications work by combining the effects of beta-blockers, which slow your heart rate and lower blood pressure, with thiazide-like diuretics, which help your body get rid of extra salt and water, which decreases your blood pressure. These medications are available in oral form. An example of this combination is atenolol / chlorthalidone (Tenoretic).