apomorphine

Nausea and vomiting is a very common side effect of apomorphine (Apokyn). To prevent this, your provider might prescribe trimethobenzamide (Tigan), an antiemetic medication. This particular medication was used in clinical trials with apomorphine (Apokyn). Don't take other anti-nausea medications unless directed by your healthcare provider. They might interact with apomorphine (Apokyn).

• Risk factors: History of drowsiness | History of sleep problems | Taking sedatives or medications that make you drowsy

Medications like apomorphine (Apokyn) that raise the levels of dopamine can cause you to suddenly fall asleep, even if you don't feel sleepy. Avoid driving or doing activities that require you to focus until you know how this medication affects you. Take extra care if you have a history of sleepiness or falling asleep suddenly in the past. If you feel very sleepy during the daytime or if you fall asleep during activities where you need to concentrate, let your provider know, because they might have you stop apomorphine (Apokyn).

• Risk factors: When the dose of apomorphine (Apokyn) is raised

Sometimes, people taking apomorphine (Apokyn) have a sudden drop in blood pressure when they stand up from a sitting or lying down position. This can lead to serious falls or fainting. You might notice the drop in blood pressure more often when your provider raises your apomorphine (Apokyn) dose. Let your provider know if you have a fall, faint, or experience dizziness when changing positions. It can help if you rise slowly and steady yourself on a firm object, like a sturdy nightstand, whenever you're getting up.

• Risk factors: History of certain mental health conditions

Apomorphine (Apokyn) and medications that raise your dopamine levels can cause hallucinations and changes in behavior and thinking. Some people had paranoia, delusions, confusion, aggressive behavior, uneasiness, and less awareness of your surroundings. If you have a history of mental health conditions, apomorphine (Apokyn) might not be right for you, since this medication can worsen your condition. Let your provider know if you experience hallucinations or any changes in behavior or thinking while taking apomorphine (Apokyn); they might need to lower your dose, which can help.

Some people had lower impulse control while taking PD medications, such as apomorphine (Apokyn). This can include strong sexual or gambling urges, urges to spend a lot of money, and binge eating. Talk to your provider if these urges start to have a negative impact on your life. Lowering your dose or stopping the medication can help.

• Risk factors: History of heart or blood flow problems

Some people experienced chest pain, heart attacks, and other serious heart problems during apomorphine (Apokyn) clinical trials. Sometimes, these events happened a few hours after a dose was given. Seek medical help if you ever have chest pain, dizziness, or shortness of breath. Let your provider know if you ever feel an irregular heartbeat. Let your care team know your full medical history. Apomorphine (Apokyn) might not be appropriate for people at high risk for certain heart and blood flow conditions.

It's rare, but some men taking apomorphine (Apokyn) experienced priapism (long painful erections). Seek medical help if you have an erection that lasts longer than 4 hours.