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Vonjo

Vonjo Side Effects

Allison Baxley, PharmD, BCOPCydnee Ng, PharmD
Reviewed by Allison Baxley, PharmD, BCOP, Cydnee Ng, PharmD
Last reviewed on July 8, 2025

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Diarrhea (48%)
  • Low platelets (34%)
  • Nausea (32%)
  • Anemia (24%)
  • Swelling in the hands, ankles, or feet (20%)
  • Vomiting (19%)
  • Dizziness (15%)
  • Fever (15%)

Less Common Side Effects

Vonjo serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Bleeding: bruising that you can’t explain, bleeding that doesn’t stop, getting nosebleeds often, blood in urine, blood in stool
  • Changes in heart rhythm: lightheadedness, blurry vision, fainting, passing out
  • Blood clot: swelling in one arm or one leg, sudden and severe chest pain
  • Heart attack: chest pain that spreads to the arm or jaw, pressure in the chest, sweating, shortness of breath, nausea
  • Stroke: sudden and severe headache, weakness on one side of the body, drooping face, trouble speaking, trouble seeing, trouble walking, confusion
  • Infection: a body temperature of 100.4ºF or higher, chills, body aches, cough
When do Vonjo possible side effects begin and end?
Time passed since treatment started:
M
H
D
W
M
Risk of diarrhea
Risk of low platelets
Risk of bleeding
Seek immediate medical care if you experience this side effect.
If a line continues to the right, you'll likely keep experiencing this side effect once it starts.

Source: DailyMed

The following Vonjo side effects have also been reported

Side effects that you should report to your care team as soon as possible:

  • Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
  • Bleeding—bloody or black, tar-like stools, vomiting blood or brown material that looks like coffee grounds, red or dark brown urine, small red or purple spots on skin, unusual bruising or bleeding
  • Blood clot—pain, swelling, or warmth in the leg, shortness of breath, chest pain
  • Heart attackpain or tightness in the chest, shoulders, arms, or jaw, nausea, shortness of breath, cold or clammy skin, feeling faint or lightheaded
  • Heart rhythm changes—fast or irregular heartbeat, dizziness, feeling faint or lightheaded, chest pain, trouble breathing
  • Infection—fever, chills, cough, sore throat, wounds that don't heal, pain or trouble when passing urine, general feeling of discomfort or being unwell
  • Severe or prolonged diarrhea
  • Stroke—sudden numbness or weakness of the face, arm, or leg, trouble speaking, confusion, trouble walking, loss of balance or coordination, dizziness, severe headache, change in vision
  • Unusual bruising or bleeding

Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome):

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