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Caprelsa

Caprelsa Side Effects

Belinda Li, PharmD, BCOPDaisy Chau, PharmD
Reviewed by Belinda Li, PharmD, BCOP, Daisy Chau, PharmD
Last reviewed on November 13, 2023

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Diarrhea (57%)
  • Rash (53%)
  • Acne (35%)
  • High blood pressure (33%)
  • Nausea (33%)
  • Headache (26%)
  • Fatigue (24%)
  • Upper respiratory infection (23%)
  • Poor appetite (21%)
  • Stomach pain (21%)

Less Common Side Effects

  • Dry mouth
  • Indigestion
  • Itching
  • Nail changes
  • Hair loss
  • Blurred vision
  • Depression
  • Muscle spasms
  • Eye problems

Caprelsa serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Abnormal heart rhythm (QT prolongation): chest pounding, short of breath, chest pain, feeling faint, lightheaded, dizzy, heart beating fast
  • Severe allergic or skin reactions: rash, peeling of skin, hives, trouble breathing, swollen lymph nodes
  • Lung damage (interstitial lung disease): shortness of breath, fever, lasting dry cough
  • Stroke: weakness or numbness in your arm, legs, or face on one side of the body, trouble speaking, blurred vision, dizziness, loss of balance, trouble walking, confusion
  • Serious bleeds: bleeding or bruises that doesn’t stop or go away, large amount of bleeding, blood in the urine, bloody or black and tarry stool
  • Heart failure: swelling, shortness of breath, coughing, wheezing, fatigue, weight changes
  • Posterior reversible encephalopathy syndrome (PRES): severe headaches, seizures, confusion, changes in vision, difficulty staying awake, trouble speaking
  • Kidney problems: swelling, less urination, nausea, fatigue, metallic taste changes, cramps

Source: DailyMed

The following Caprelsa side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Bleeding gums

blindness

blistering, crusting, irritation, itching, or reddening of the skin

blurred vision

body aches or pain

chest pain or tightness

chills

cloudy urine

confusion

cough

coughing up blood

difficulty with breathing or swallowing

dizziness

ear congestion

fainting

fever

headache

increased menstrual flow or vaginal bleeding

increased sensitivity of the skin to sunlight

irregular heartbeat, recurrent

loss of voice

muscle cramps in the hands, arms, feet, legs, or face

nervousness

nosebleeds

numbness and tingling around the mouth, fingertips, or feet

paralysis

pounding in the ears

prolonged bleeding from cuts

red or black, tarry stools

red or dark brown urine

seizures

severe sunburn

slow or fast heartbeat

sneezing

sore throat

stomach cramps or pain

stuffy or runny nose

tenderness

tremor

trouble breathing

unusual tiredness or weakness, severe

watery or bloody diarrhea

Less common

Blue lips, fingernails, or skin

dilated neck veins

extreme tiredness or weakness

infection from breathing foreign substance into the lungs

irregular heartbeat

irregular, fast or slow, or shallow breathing

lightheadedness

swelling of the face, fingers, feet, or lower legs

weight gain

Rare

Bloating

constipation

decreased urine output

indigestion

loss of appetite

nausea

pains in the stomach, side, or abdomen, possibly radiating to the back

yellow eyes or skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Belching

blemishes on the skin

change in or loss of taste

cracked, dry, or scaly skin

cracks in the skin

decreased weight

depression

discoloration of the fingernails or toenails

dry mouth or skin

hair loss or thinning of the hair

heartburn

lack or loss of strength

loosening of the fingernails

loss of heat from the body

muscle aches or spasms

pimples

rash with flat lesions or small raised lesions on the skin

redness or other discoloration of the skin

redness or soreness around the fingernails

stomach discomfort or upset

trouble sleeping

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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