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Semprex-D

acrivastine / pseudoephedrine
Used for Allergic Rhinitis, Nasal Congestion

Semprex-D (acrivastine / pseudoephedrine) is a combination of two medications used to treat allergy symptoms, such as runny or stuffy nose, sneezing, and itchy eyes. It's no longer available in the United States because it has been discontinued.

Reviewed by:
reviewerKristianne Hannemann, PharmD
reviewerMichelle Nguyen, PharmD
Last reviewed on February 6, 2022
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What is Semprex-D (acrivastine / pseudoephedrine)?

Drug facts

Common Brands
Semprex-D(brand no longer available)
Drug ClassAntihistamine / Decongestant
Controlled Substance ClassificationNot a controlled medication
Generic StatusNo lower-cost generic available
AvailabilityDiscontinued
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Common questions about Semprex-D (acrivastine / pseudoephedrine)

Semprex-D (acrivastine / pseudoephedrine) is a combination of two medications. Acrivastine is an antihistamine that works by blocking histamine, a natural chemical in your body that causes congestion (stuffy nose), runny nose, sneezing, and watery eyes. Pseudoephedrine is a decongestant that works by narrowing your blood vessels so less fluid leaks out. This causes less pressure in your sinuses and congestion in your nose.

No, Semprex-D (acrivastine / pseudoephedrine) is no longer available as a brand or generic in the United States because it has been discontinued.

Semprex-D (acrivastine / pseudoephedrine) was discontinued by the manufacturer due to business reasons. It wasn't discontinued because of safety issues.

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Semprex-D (acrivastine / pseudoephedrine) dosage

Typical dosage for Semprex-D (acrivastine / pseudoephedrine)

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Interactions between Semprex-D (acrivastine / pseudoephedrine) and other drugs

Semprex-D (acrivastine / pseudoephedrine) may interact with certain medications or supplements. Always let your doctor and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking. The list below does not include all possible drug interactions with Semprex-D (acrivastine / pseudoephedrine). Please note that only the generic name of each medication is listed below.

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking any of these medicines, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using medicines in this class with any of the following medicines is not recommended. Your doctor may decide not to treat you with a medication in this class or change some of the other medicines you take.

Using medicines in this class with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

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