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Oxaprozin Coupon - Oxaprozin 600mg tablet

oxaprozin

Generic Daypro
Used for Rheumatoid Arthritis, Osteoarthritis
Used for Rheumatoid Arthritis, Osteoarthritis

Oxaprozin (Daypro) is a prescription nonsteroidal anti-inflammatory drug (NSAID) that can help relieve arthritis pain in adults and children age 6 years and older. It's taken by mouth once per day. As with other NSAIDs, it can have side effects like stomach pain and heartburn.

Reviewed by:
reviewer
Robert Chad Hakim, PharmD, BCCCP
reviewer
Allison Gourley, PharmD
Last reviewed on March 26, 2023
BasicsSide effectsPros & consPharmacist tipsFAQsWarningsDosageInteractionsCostContraindicationsAlternativesLatest newsImagesReferencesPricesMedicare
basics-icon

What is Oxaprozin (Daypro)?

What is Oxaprozin (Daypro) used for?

  • Osteoarthritis

  • Rheumatoid arthritis

  • Juvenile rheumatoid arthritis

How Oxaprozin (Daypro) works

Oxaprozin (Daypro) is a nonsteroidal anti-inflammatory drug (NSAID). It works by blocking proteins in your body (called cyclooxygenase or COX) that cause inflammation, pain, and swelling.

Are you looking for information on prazosin (Minipress) instead?

Drug Facts

Common BrandsDaypro
Drug ClassNSAID
Controlled Substance ClassificationNot a controlled medication
Generic StatusLower-cost generic available
AvailabilityPrescription only
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Avg retail price
$203.45(save 79.36%)
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$41.99
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What are the side effects of Oxaprozin (Daypro)?

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Stomach pain or discomfort
  • Upset stomach or indigestion
  • Constipation
  • Diarrhea
  • Nausea
  • Rash

Other Side Effects

  • Loss of appetite
  • Vomiting
  • Gas
  • Dizziness
  • Headache
  • Ringing in ears
  • Anemia

Serious Side Effects

Contact your healthcare provider immediately if you experience any of the following.
  • Stomach bleeding: feeling faint, vomiting blood, bloody or dark stools, severe stomach pain or discomfort
  • Heart attack: chest pain or tightness, pain that radiates up to your shoulder, arm, neck, or jaw
  • Stroke: chest pain, trouble breathing, weakness in one part of your body or face, slurred speech
  • Heart failure: difficulty breathing, swelling, fast heartbeat
  • Liver problems: swelling of your stomach, yellowing of your skin or the whites of your eyes, confusion, dark or brown urine
  • Kidney problems: tiredness, dry and itchy skin, low appetite, urinating less than usual, foamy or bloody urine, muscle cramps
  • Allergic reactions: hives, rash, blisters, swelling of the lips or tongue, difficulty breathing
  • Serious skin reactions: skin reddening, blisters, rash

Source: DailyMed

The following side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Skin rash

Less common

Bloating

bloody or black, tarry stools

burning upper abdominal or stomach pain

burning while urinating

cloudy urine

constipation

decrease in urine output or decrease in urine-concentrating ability

diarrhea

difficult or painful urination

frequent urination

headache

heartburn

indigestion

itching skin

loss of appetite

nausea or vomiting

pale skin

severe abdominal or stomach pain, cramping, or burning

severe and continuing nausea

swelling

troubled breathing with exertion

unusual bleeding or bruising

unusual tiredness or weakness

vomiting of blood or material that looks like coffee grounds

weight loss

Rare

Agitation

bleeding gums

blistering, peeling, or loosening of the skin

blurred vision

body aches or pain

burning feeling in chest or stomach

changes in blood pressure

chest pain

clay-colored stools

coma

confusion

cough or hoarseness

cracks in the skin

dark urine

depression

difficult or labored breathing

difficulty swallowing

dilated neck veins

dizziness

ear congestion

extreme fatigue

fainting

feeling of discomfort

fever or chills

fluid-filled skin blisters

high fever

hives or welts

hostility

increased sensitivity of the skin to sunlight

increased thirst

increased volume of pale, dilute urine

inflammation of the joints

irregular, fast or slow, or shallow breathing

joint or muscle pain

large, flat, blue or purplish patches in the skin

large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs

lethargy

light-colored stools

lightheadedness

loss of heat from the body

loss of voice

lower back or side pain

muscle aches

muscle twitching

noisy breathing

pain or burning in the throat

pain or tenderness around the eyes and cheekbones

pale or blue lips, fingernails, or skin

pinpoint red or purple spots on the skin

pounding in the ears

puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue

rapid weight gain

red skin lesions, often with a purple center

red, irritated eyes

redness or other discoloration of the skin

redness, swelling, or soreness of tongue

scaly skin

seizures

severe sunburn

skin thinness

slow, fast, irregular, pounding, or racing heartbeat or pulse

sneezing

sore throat

sores, ulcers, or white spots on the lips or tongue or inside the mouth

stuffy or runny nose

stupor

swelling of the face, fingers, feet, or lower legs

swelling or inflammation of the mouth

swollen lymph glands

tenderness in the stomach area

tightness in the chest

unpleasant breath odor

upper right abdominal or stomach pain

yellow eyes or skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Acid or sour stomach

belching

stomach discomfort

Less common

Continuing ringing or buzzing or other unexplained noise in the ears

excess air or gas in the stomach or intestines

hearing loss

passing gas

relaxed and calm

sleepiness or unusual drowsiness

trouble sleeping

Rare

Burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings

burning, dry, or itching eyes

change in taste

decreased hearing

discharge, excessive tearing

dry mouth

feeling of constant movement of self or surroundings

general feeling of discomfort or illness

lack or loss of strength

redness, pain, swelling of the eye, eyelid, or inner lining of the eyelid

sensation of spinning

shakiness in the legs, arms, hands, feet

trembling or shaking of the hands or feet

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

pros-and-cons

Pros and cons of Oxaprozin (Daypro)

thumbs-up

Pros

Works well to treat arthritis pain

Taken once per day

Can used for both adults and children as young as 6 years old

thumbs-down

Cons

Common to have stomach upset

Has risk of stomach bleeding

Only available as a tablet

pharmacist-tips

Pharmacist tips for Oxaprozin (Daypro)

pharmacist

  • You can take oxaprozin (Daypro) with or without food. But it's best to take it with food or milk to prevent getting an upset stomach as a side effect of the medication. Just know that food can slow how long it takes for your body to absorb the medication. This means it might take a little longer for the pain relief effects of oxaprozin (Daypro) to kick in if you take it with food.

    • Avoid alcohol while taking oxaprozin (Daypro) because it can raise your risk for stomach bleeds and stomach ulcers.

      • Don't take oxaprozin (Daypro) with other NSAIDs, such as ibuprofen (Motrin, Advil). Doing so puts you at higher risk for stomach bleeds. NSAIDs are commonly found in over-the-counter pain and cold medications. Talk with your healthcare provider or pharmacist if you're not sure whether you're already taking an NSAID.

        • Oxaprozin (Daypro) can interact with a lot of other common medications, such as blood pressure medications, blood thinners (including aspirin), and certain antidepressants. Make sure to tell your provider about all of the medications you're taking or planning to take before starting oxaprozin (Daypro). They can make sure your medications are safe for you to take together.

          • Oxaprozin (Daypro) can make your skin more sensitive to the sun or ultraviolet (UV) light. This means you can get sunburns more easily than usual. To protect your skin, make sure to wear sunscreen when going outside and wear long-sleeved clothing. Also avoid being exposed to light or sun for a long time.

            • Store oxaprozin (Daypro) up and away from children and pets so they're less likely to reach and accidentally take the medication. If you think your child accidentally took the medication, call a Poison Control Center right away at 1-800-222-1222.

              faqs

              Frequently asked questions about Oxaprozin (Daypro)

              Can I take over-the-counter pain medications while also taking oxaprozin (Daypro)?
              If you need additional pain relief while taking oxaprozin (Daypro), it's generally safe to take over-the-counter acetaminophen (Tylenol) as long as you don't have liver problems. Make sure to ask your provider about how much acetaminophen (Tylenol) you can take. But, don't take other over-the-counter NSAIDs, like ibuprofen (Advil, Motrin) or naproxen (Aleve), because they belong to the same medication class as oxaprozin (Daypro). Taking more than one NSAID can raise your risk for severe side effects, such as heart problems, kidney problems, or bleeds. Make sure to check the manufacturer label carefully to see if a specific product contains an NSAID. Ask your provider or pharmacist if you're not sure if you can take a particular over-the-counter pain medication with oxaprozin (Daypro).
              Can I use oxaprozin (Daypro) only when I need it to relieve pain?
              Oxaprozin (Daypro) isn't typically used as needed for arthritis pain. It's usually taken every day on a regular basis. If you feel that you don't need to take oxaprozin (Daypro) every day, talk to your provider. They can discuss options that best fit your needs, such as the possibility of taking oxaprozin (Daypro) as needed or switching to a different pain medication.
              Can I drink alcohol while I'm taking oxaprozin (Daypro)?
              It's recommended that you limit the amount of alcohol you drink if you're taking oxaprozin (Daypro). This is because drinking alcohol while taking oxaprozin (Daypro) can raise your risk for stomach bleeds. But if you have other conditions that put you at higher risk for bleeds (e.g., older age, taking a blood thinner), your provider might advise you to avoid alcohol completely. Speak with your provider about your alcohol consumption and whether it's safe for you to drink alcohol during treatment with oxaprozin (Daypro).
              Is it safe to take oxaprozin (Daypro) if I'm pregnant?
              It's not clear whether or not oxaprozin (Daypro) is safe to take during early pregnancy. But the FDA recommends that you avoid taking oxaprozin (Daypro) during the second half of pregnancy (week 20 of pregnancy or later) because it might cause harm to your unborn baby or complications during delivery. If you're pregnant, speak with your provider about safer medications you can take for arthritis pain.
              Is oxaprozin (Daypro) safe to take while breastfeeding?
              There haven't been any studies done to know for sure whether or not oxaprozin (Daypro) is safe to take while breastfeeding. It's recommended to use a different medication to relieve arthritis pain while breastfeeding. Discuss with your provider about the risks and benefits of using oxaprozin (Daypro) while breastfeeding to make sure this medication is safe for you and your baby.
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              warings-icon

              What are the risks and warnings for Oxaprozin (Daypro)?

              Oxaprozin (Daypro) can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.

              risk-warning

              Stomach bleeding

              • Risk factors: Older adult | History of stomach bleeding or bleeding problems | Liver problems | Taking other medications that raise your risk of bleeds | Drinking alcohol | Smoking | Taking oxaprozin (Daypro) for a long time

                Oxaprozin (Daypro), like all NSAIDs, raises your risk for stomach ulcers (sores) and bleeds. Stomach bleeding is a dangerous condition that requires treatment right away. Make sure to tell your provider or pharmacist about all of your medical conditions and medications before starting oxaprozin (Daypro) so they can talk with you about your risk for stomach bleeding. If you're feeling faint, vomiting blood, have bloody or dark stools, or have severe stomach pain or discomfort that doesn't go away while taking oxaprozin (Daypro), get medical attention right away.

                risk-warning

                Heart attack and stroke

                • Risk factors: Heart problems | Taking higher doses of oxaprozin (Daypro) | Taking oxaprozin (Daypro) for a long time | Past or planned heart surgery

                  Oxaprozin (Daypro) can raise your risk of having blood clots, which can cause a heart attack or stroke. Your provider will prescribe the lowest dose of oxaprozin (Daypro) for the shortest period of time possible. If you have heart problems, talk to your healthcare provider before starting this medication. Don't take oxaprozin (Daypro) if you had, or will have, heart surgery. Call 911 or get medical help right away if you experience chest pain, shortness of breath, weakness on one side of your body, or trouble speaking or walking.

                  risk-warning

                  High blood pressure and heart failure

                  • Risk factors: Heart problems

                    Oxaprozin (Daypro) can cause your body to hold onto extra fluid, which can raise your blood pressure or put you at risk for heart failure. Tell your provider if you have a history of heart problems or are taking blood pressure medications before starting oxaprozin (Daypro) to make sure it's safe for you. Your provider will check for heart problems before they prescribe this medication to you. If you experience unexplained fainting, chest pain with physical activity, or irregular heartbeat while taking oxaprozin (Daypro), contact your provider.

                    risk-warning

                    Kidney damage

                    • Risk factors: Older adult | Kidney or liver problems | Heart failure | High blood sugar | Sepsis | Having high amounts of certain proteins in blood (paraproteinemia) | Not enough fluids in the body (dehydration) | Taking other medications that can cause kidney problems

                      Oxaprozin (Daypro) can cause kidney problems. Your risk is higher if you have certain factors like older age, certain medical problems like diabetes, or you're taking medications that can cause kidney problems. Your provider might order blood tests to monitor your kidney health before and during treatment with oxaprozin (Daypro). If your kidney health worsens, your provider might stop your oxaprozin (Daypro) treatment. Contact your provider if you develop any signs or symptoms of kidney failure, including changes in your need to urinate, tiredness, dry and itchy skin, low appetite, and muscle cramps.

                      risk-warning

                      Liver problems

                      • Risk factors: History of liver problems

                        Although rare, oxaprozin (Daypro) can cause serious liver problems that can lead to liver failure. Get medical attention right away if you notice swelling of your stomach, stomach pain, yellowing of your skin or the whites of your eyes, stool changes (black, tarry, or bloody stools), nausea, vomiting, confusion, or dark or brown urine. You might need to stop using the medication to prevent further liver damage.

                        risk-warning

                        Severe allergic reactions

                        • Risk factors: Aspirin allergy | NSAID allergy

                          Severe allergic reactions to oxaprozin (Daypro) are possible, including life-threatening reactions like facial swelling, shock, and anaphylaxis. Let your provider know if you have an allergy to aspirin or other NSAIDs before starting oxaprozin (Daypro). If you notice hives, rash, red skin, swelling of the lips or tongue, or difficulty breathing after using oxaprozin (Daypro), call for medical help as soon as possible.

                          Although rare, oxaprozin (Daypro) can cause serious skin reactions, such as rash, blisters, skin reddening, or skin peeling. If you notice changes in your skin, stop using oxaprozin (Daypro) and get medical attention right away.

                          risk-warning

                          Not for use in pregnant or breastfeeding females

                          If you're pregnant or breastfeeding, talk to your provider first about the risk and benefits of oxaprozin (Daypro) before using this medication. Oxaprozin (Daypro) can cause harm to your unborn baby or complications during delivery if taken during the second half of pregnancy.

                          dosage

                          Oxaprozin (Daypro) dosage forms

                          The average cost for 60 tablets of 600mg of Oxaprozin (Daypro) is $41.99 with a free GoodRx coupon. This is 79.36% off the average retail price of $203.45.
                          capsule
                          Capsule
                          DosageQuantityPrice as low asPrice per unit
                          300mg60 capsules$328.03$5.47
                          tablet
                          Tablet
                          DosageQuantityPrice as low asPrice per unit
                          600mg60 tablets$41.99$0.70

                          Typical dosing for Oxaprozin (Daypro)

                          • Osteoarthritis and rheumatoid arthritis: The typical dose is 1,200 mg (two 600 mg tablets) by mouth once per day.

                          • Juvenile rheumatoid arthritis (children ages 6 to 16): The dose depends on your child's body weight. The typical dose is either 600 mg, 900 mg, or 1,200 mg by mouth once per day.

                          The maximum total daily dose for adults is 1,800 mg or 26 mg/kg of your body weight, whichever is lower, separated into smaller doses throughout the day. The maximum daily dose for children is 1,200 mg per day.

                          interactions

                          Interactions between Oxaprozin (Daypro) and other drugs

                          Oxaprozin (Daypro) may interact with certain medications or supplements. Always let your doctor and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking. The list below does not include all possible drug interactions with Oxaprozin (Daypro). Please note that only the generic name of each medication is listed below.

                          Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

                          Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

                          Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

                          drug-cost

                          How much does Oxaprozin (Daypro) cost?

                          To access savings, use a GoodRx coupon and pay just a fraction of the retail price.
                          Daypro (brand)
                          GoodRx lowest price

                          $41.99

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                          Oxaprozin (Daypro) (generic)
                          GoodRx lowest price

                          $41.99

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                          contraindications-icon

                          Oxaprozin (Daypro) contraindications

                          Contraindications are specific health conditions or situations in which a person should not take a medication due to safety concerns. If you have any of the following conditions or if any of the following apply to you, let your healthcare provider know because Oxaprozin (Daypro) will not be safe for you to take.
                          alternatives

                          What are alternatives to Oxaprozin (Daypro)?

                          There are a number of medications that your doctor can prescribe in place of Oxaprozin (Daypro). Compare a few possible alternatives below.
                          Oxaprozin (Daypro)
                          Used for:

                          • Osteoarthritis

                          • Rheumatoid arthritis

                          • Juvenile rheumatoid arthritis

                          $41.99 Lowest GoodRx priceView Prices
                          Diclofenac
                          Used for:

                          • Mild to moderate pain

                          • Osteoarthritis

                          • Rheumatoid arthritis

                          • Ankylosing spondylitis (arthritis of the spine)

                          • Migraine attacks

                          • Menstrual cramps

                          $11.95 Lowest GoodRx priceView Prices
                          Meloxicam
                          Used for:
                          $6.84 Lowest GoodRx priceView Prices
                          images

                          Oxaprozin (Daypro) images

                          White Oblong E141 - Oxaprozin 600mg Tablet
                          This medicine is White, Oblong, Scored Tablet Imprinted With "E141".White Oblong E141 - Oxaprozin 600mg Tablet
                          Yellow Oval 01 70 And C - Oxaprozin 600mg Tablet
                          This medicine is Yellow, Oval, Scored Tablet Imprinted With "C" And "01 70".Yellow Oval 01 70 And C - Oxaprozin 600mg Tablet
                          White Oblong 391 - Oxaprozin 600mg Tablet
                          This medicine is White, Oblong, Scored Tablet Imprinted With "391".White Oblong 391 - Oxaprozin 600mg Tablet
                          White Oblong Daypro And 13 81 - Oxaprozin 600mg Tablet
                          This medicine is White, Oblong, Scored Tablet Imprinted With "13 81" And "Daypro".White Oblong Daypro And 13 81 - Oxaprozin 600mg Tablet
                          White Oblong 46 And C E - Oxaprozin 600mg Tablet
                          This medicine is White, Oblong, Scored Tablet Imprinted With "C E" And "46".White Oblong 46 And C E - Oxaprozin 600mg Tablet
                          White Oblong Aa59 - Oxaprozin 600mg Tablet
                          This medicine is White, Oblong, Scored Tablet Imprinted With "Aa59".White Oblong Aa59 - Oxaprozin 600mg Tablet

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                          References

                          Best studies we found

                          Arthritis Foundation. (n.d.). Juvenile Idiopathic Arthritis (JIA).

                          Baudax Bio. (2022). ANJESO- meloxicam injection [package insert]. DailyMed.

                          Drugs and Lactation Database (LactMed). (2018). Oxaprozin. National Institute of Child Health and Human Development.

                          View All References (9)

                          Emerald Therapeutics. (2022). MELOXICAM suspension [package insert]. DailyMed.

                          Greenstone. (2020). OXAPROZIN tablet, film coated [package insert]. DailyMed.

                          Lupin Pharmaceuticals. (2022). MELOXICAM capsule [package insert]. DailyMed.

                          Miller, L. G. (1992). Oxaprozin: A once-daily nonsteroidal anti-inflammatory drug. Clinical Pharmacy.

                          National Heart, Lung, and Blood Institute. (2022). What is coronary artery bypass grafting?

                          National Kidney Foundation. (2020). 10 signs you may have kidney disease.

                          U.S. Food and Drug Administration. (2016). FDA drug safety communication: FDA warns of rare but serious skin reactions with the pain reliever/fever reducer acetaminophen.

                          U.S. Food and Drug Administration. (2020). Nonsteroidal anti-inflammatory drugs (NSAIDs): Drug safety communication - avoid use of NSAIDs in pregnancy at 20 weeks or later.

                          Zydus Pharmaceuticals USA. (2022). MELOXICAM tablet [package insert]. DailyMed.

                          GoodRx Health has strict sourcing policies and relies on primary sources such as medical organizations, governmental agencies, academic institutions, and peer-reviewed scientific journals. Learn more about how we ensure our content is accurate, thorough, and unbiased by reading our editorial guidelines.
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