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Oxaprozin Coupon - Oxaprozin 300mg capsule

oxaprozin

Generic Coxanto
Used for Rheumatoid Arthritis, Osteoarthritis
Used for Rheumatoid Arthritis, Osteoarthritis

Oxaprozin (Coxanto) is a non-steroidal anti-inflammatory drug (NSAID). It's used to relieve osteoarthritis (OA) and rheumatoid arthritis (RA) pain in people ages 6 years and older. Oxaprozin (Coxanto) comes as capsules that are taken by mouth once daily. Side effects of this medication include stomach pain, indigestion, or rash. Oxaprozin (Coxanto) is only available by prescription.

Reviewed by:
reviewer
Robert Chad Hakim, PharmD, BCCCP
reviewer
Allison Gourley, PharmD
Last reviewed on August 1, 2024
BasicsSide effectsPros & consPharmacist tipsFAQsWarningsDosageInteractionsCostContraindicationsAlternativesLatest newsImagesReferencesPricesMedicare
basics-icon

What is Oxaprozin (Coxanto)?

What is Oxaprozin (Coxanto) used for?

How Oxaprozin (Coxanto) works

Oxaprozin (Coxanto) is a non-steroidal anti-inflammatory drug (NSAID). It lowers inflammation, pain, and swelling by blocking proteins in your body called cyclooxygenase or COX.

Are you looking for information on oxaprozin (Daypro) tablets instead?

Drug Facts

Common BrandsCoxanto
Drug ClassNSAID
Controlled Substance ClassificationNot a controlled medication
Generic StatusLower-cost generic available
AvailabilityPrescription only
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What are the side effects of Oxaprozin (Coxanto)?

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Upset stomach or indigestion (3% or more)
  • Constipation (3% or more)
  • Diarrhea (3% or more)
  • Nausea (3% or more)
  • Rash (3% or more)

Other Side Effects

  • Headache
  • Dizziness
  • Ringing in ears
  • Loss of appetite
  • Vomiting
  • Passing gas
  • Itching
  • Stomach pain
  • Stomach ulcers
  • Swelling

Serious Side Effects

Contact your healthcare provider immediately if you experience any of the following.
  • Heart attack: dizziness, tiredness, cold sweat, trouble breathing, chest pain or tightness, anxiety
  • Stroke: tiredness, lightheadedness, blurred vision, difficulty speaking, difficulty walking, weakness on one side of the body
  • Stomach bleeds: blood in your vomit, stool that looks like black coffee grounds, pain in your stomach that doesn't go away
  • Heart failure: trouble breathing, tiredness, swelling in your body, sudden weight gain
  • Liver damage: fever, chills, fatigue, nausea, vomiting, yellowing of the skin or whites of the eyes, clay-colored stool, dark urine
  • Kidney damage and high potassium: nausea, muscle weakness, tingling sensations in your muscles, changes in how much you urinate
  • Severe asthma attack: chest pain, cough, difficulty breathing, wheezing
  • Serious allergic or skin reaction: fever, rash, body aches, cough, swelling of the face, peeling skin, painful blisters all over your body

Source: DailyMed

The following side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Skin rash

Less common

Bloating

bloody or black, tarry stools

burning upper abdominal or stomach pain

burning while urinating

cloudy urine

constipation

decrease in urine output or decrease in urine-concentrating ability

diarrhea

difficult or painful urination

frequent urination

headache

heartburn

indigestion

itching skin

loss of appetite

nausea or vomiting

pale skin

severe abdominal or stomach pain, cramping, or burning

severe and continuing nausea

swelling

troubled breathing with exertion

unusual bleeding or bruising

unusual tiredness or weakness

vomiting of blood or material that looks like coffee grounds

weight loss

Rare

Agitation

bleeding gums

blistering, peeling, or loosening of the skin

blurred vision

body aches or pain

burning feeling in chest or stomach

changes in blood pressure

chest pain

clay-colored stools

coma

confusion

cough or hoarseness

cracks in the skin

dark urine

depression

difficult or labored breathing

difficulty swallowing

dilated neck veins

dizziness

ear congestion

extreme fatigue

fainting

feeling of discomfort

fever or chills

fluid-filled skin blisters

high fever

hives or welts

hostility

increased sensitivity of the skin to sunlight

increased thirst

increased volume of pale, dilute urine

inflammation of the joints

irregular, fast or slow, or shallow breathing

joint or muscle pain

large, flat, blue or purplish patches in the skin

large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs

lethargy

light-colored stools

lightheadedness

loss of heat from the body

loss of voice

lower back or side pain

muscle aches

muscle twitching

noisy breathing

pain or burning in the throat

pain or tenderness around the eyes and cheekbones

pale or blue lips, fingernails, or skin

pinpoint red or purple spots on the skin

pounding in the ears

puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue

rapid weight gain

red skin lesions, often with a purple center

red, irritated eyes

redness or other discoloration of the skin

redness, swelling, or soreness of tongue

scaly skin

seizures

severe sunburn

skin thinness

slow, fast, irregular, pounding, or racing heartbeat or pulse

sneezing

sore throat

sores, ulcers, or white spots on the lips or tongue or inside the mouth

stuffy or runny nose

stupor

swelling of the face, fingers, feet, or lower legs

swelling or inflammation of the mouth

swollen lymph glands

tenderness in the stomach area

tightness in the chest

unpleasant breath odor

upper right abdominal or stomach pain

yellow eyes or skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Acid or sour stomach

belching

stomach discomfort

Less common

Continuing ringing or buzzing or other unexplained noise in the ears

excess air or gas in the stomach or intestines

hearing loss

passing gas

relaxed and calm

sleepiness or unusual drowsiness

trouble sleeping

Rare

Burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings

burning, dry, or itching eyes

change in taste

decreased hearing

discharge, excessive tearing

dry mouth

feeling of constant movement of self or surroundings

general feeling of discomfort or illness

lack or loss of strength

redness, pain, swelling of the eye, eyelid, or inner lining of the eyelid

sensation of spinning

shakiness in the legs, arms, hands, feet

trembling or shaking of the hands or feet

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

pros-and-cons

Pros and cons of Oxaprozin (Coxanto)

thumbs-up

Pros

Taken by mouth

Taken once per day

Available as generic capsules

thumbs-down

Cons

Might need to take 2 to 4 capsules at a time for a single dose

Not available as a liquid

Not meant to be taken long term because risk of side effects, like blood clots or stomach bleeding

pharmacist-tips

Pharmacist tips for Oxaprozin (Coxanto)

pharmacist

  • You can take oxaprozin (Coxanto) with or without food. But you're recommended to take it with food or milk because doing so can help prevent stomach irritation.

    • Don't crush, chew, or open the oxaprozin (Coxanto) capsules. If you're having trouble swallowing the capsules, contact your healthcare team. You might need to be switched to a different medication.

      • Avoid drinking alcohol while taking oxaprozin (Coxanto). Doing so can raise your risk for stomach bleeds and stomach ulcers.

        • Don't take oxaprozin (Coxanto) with other NSAIDs, such as ibuprofen (Motrin, Advil). Doing so puts you at higher risk for side effects, including stomach bleeds. NSAIDs are commonly found in over-the-counter pain and cold medications. Talk with your pharmacist if you're not sure whether you're already taking an NSAID.

          • Oxaprozin (Coxanto) can interact with many medications, including blood pressure medications, blood thinners (including aspirin), and certain steroids. Tell your healthcare team about all of the medications you're taking or planning to take before starting oxaprozin (Coxanto). They can make sure your medications are safe for you to take together.

            • Oxaprozin (Coxanto) can make your skin more sensitive to the sun or ultraviolet (UV) light. This means you can get more sunburns than usual. To protect your skin, make sure to wear sunscreen when going outside and wear long-sleeved clothing. If possible, avoid being exposed to light or sun for a long time.

              • Store oxaprozin (Coxanto) up and away from children and pets so they're less likely to reach and accidentally take the medication. If you think your child accidentally took the medication, call a Poison Control Center right away at 1-800-222-1222.

                faqs

                Frequently asked questions about Oxaprozin (Coxanto)

                What's the difference between Coxanto and Daypro?
                Both Coxanto and Daypro are brands that contain the same active ingredient, oxaprozin. Both medications are available as generics. The main difference between them is that Daypro comes as 600-mg tablets, whereas Coxanto is available as 300-mg capsules. People who need to take oxaprozin 900 mg might find it easier to take 3 capsules of Coxanto for their dose, rather than taking 1.5 tablets of Daypro because they don't need to split the tablets in half. Keep in mind that oxaprozin capsules and tablets aren't interchangeable. Talk with your healthcare team if you've more questions about either medication.
                Can I take over-the-counter pain medications while also taking oxaprozin (Coxanto)?
                It depends. You might be able to take over-the-counter acetaminophen (Tylenol) with oxaprozin (Coxanto) as long as you don't have liver problems. But you shouldn't take other over-the-counter NSAIDs, like ibuprofen (Advil, Motrin) or naproxen (Aleve), with oxaprozin (Coxanto) because taking more than one NSAID at a time can raise your risk for severe side effects, such as heart problems, kidney problems, or bleeds. Make sure to check the manufacturer label carefully to see if a specific product contains an NSAID. Ask your healthcare team if you're not sure if you can take a particular over-the-counter pain medication with oxaprozin (Coxanto).
                Can I drink alcohol while I'm taking oxaprozin (Coxanto)?
                In general, you should avoid or limit the amount of alcohol you drink if you're taking oxaprozin (Coxanto) or other NSAIDs. This is because because drinking alcohol at the same time can raise your risk for stomach bleeds. But, if you have other conditions that also raise your risk for bleeds (e.g., older age, taking a blood thinner), your provider might suggest to avoid alcohol completely.
                Is it safe to take oxaprozin (Coxanto) if I'm pregnant?
                It's not clear whether or not oxaprozin (Coxanto) is safe to take during early pregnancy. However, the FDA recommends that you avoid taking oxaprozin (Coxanto) during the second half of pregnancy (week 20 of pregnancy or later) because it might cause harm to your unborn baby or complications during delivery. If you're pregnant, speak with your obstetrician-gynecologists (OB-GYNs) about safer medications you can take for arthritis pain.
                Is oxaprozin (Coxanto) safe to take while breastfeeding?
                There haven't been any studies done to know for sure whether or not oxaprozin (Coxanto) is safe to take while breastfeeding. Because of the lack of information, you're recommended to take a different medication to relieve arthritis pain while breastfeeding. Discuss with your healthcare team about the risks and benefits of using oxaprozin (Coxanto) while breastfeeding to make sure this medication is safe for you and your baby.
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                What are the risks and warnings for Oxaprozin (Coxanto)?

                Oxaprozin (Coxanto) can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.

                risk-warning

                Stomach bleeding and ulcers

                • Risk factors: Older adult | History of stomach bleeding or bleeding problems | Liver problems | Taking other medications that raise your risk of bleeds | Drinking alcohol | Smoking | Taking oxaprozin (Coxanto) for a long time

                  Oxaprozin (Coxanto), like all NSAIDs, raises your risk for stomach ulcers (sores) and bleeds. Stomach bleeding is a dangerous condition that requires treatment right away. There are many conditions and medications that raise your risk of this problem, so speak with your healthcare team before starting oxaprozin (Coxanto). Stomach bleeding and ulcers can occur without warning or symptoms, so it's best to take the lowest possible dose of oxaprozin (Coxanto) for the shortest possible time to minimize your risk. If you notice blood in your vomit, stool that looks like black coffee grounds, or if you have pain in your stomach that doesn't go away, stop taking oxaprozin (Coxanto) and get medical help right away

                  risk-warning

                  Heart attack and stroke

                  • Risk factors: History of heart problems, including heart attack | Taking high doses of oxaprozin (Coxanto) | Taking oxaprozin (Coxanto) for a long time | History of heart bypass surgery

                    Oxaprozin (Coxanto) can raise your risk of having blood clots, which can cause a heart attack or stroke. Your healthcare team will prescribe the lowest dose of oxaprozin (Coxanto) for the shortest period of time possible to minimize your risk of blood clots. If you have heart problems, talk to your healthcare provider before starting this medication. Don't take oxaprozin (Coxanto) if you had, or will have, heart surgery. Call 911 or get medical help right away if you experience chest pain, shortness of breath, weakness on one side of your body, or trouble speaking or walking.

                    risk-warning

                    High blood pressure and heart failure

                    • Risk factors: Heart problems

                      Oxaprozin (Coxanto) can cause your body to hold onto extra fluid, which can raise your blood pressure or put you at risk for heart failure. Tell your healthcare team if you have a history of heart problems or are taking blood pressure medications before starting oxaprozin (Coxanto) to make sure it's safe for you. They might ask you to check your blood pressure more often while you're taking oxaprozin (Coxanto) and adjust the dose of your blood pressure medications as needed. If you experience unexplained fainting, chest pain with physical activity, or irregular heartbeat while taking oxaprozin (Coxanto), contact your healthcare team.

                      risk-warning

                      Kidney damage

                      • Risk factors: Older adult | Kidney or liver problems | Heart failure | High blood sugar | Sepsis | Having high amounts of certain proteins in blood (paraproteinemia) | Not enough fluids in the body (dehydration) | Taking other medications that can cause kidney problems

                        Oxaprozin (Coxanto) can cause kidney problems. Your risk is higher if you have certain factors like older age, certain medical problems like diabetes, or you're taking medications that can cause kidney problems. Your healthcare team might order blood tests to monitor your kidney health before and during treatment with oxaprozin (Coxanto). If your kidney health worsens, your provider might stop your oxaprozin (Coxanto) treatment. Contact your provider if you develop any signs or symptoms of kidney failure, including changes in your need to urinate, tiredness, dry and itchy skin, low appetite, and muscle cramps.

                        risk-warning

                        Liver problems

                        • Risk factors: History of liver problems

                          Although rare, oxaprozin (Coxanto) can cause serious liver problems, which can be life-threatening. Get medical attention right away if you notice swelling of your stomach, stomach pain, yellowing of your skin or the whites of your eyes, stool changes (black, tarry, or bloody stools), nausea, vomiting, confusion, or dark or brown urine. Your healthcare team will ask you to stop taking oxaprozin (Coxanto) while they check your liver health.

                          risk-warning

                          Severe allergic reactions

                          • Risk factors: Aspirin allergy | NSAID allergy

                            Severe allergic reactions to oxaprozin (Coxanto) are possible, including life-threatening reactions like facial swelling, shock, and anaphylaxis. Let your healthcare team know if you have an allergy to aspirin or other NSAIDs before starting oxaprozin (Coxanto). If you notice hives, rash, red skin, swelling of the lips or tongue, or difficulty breathing after using oxaprozin (Coxanto), call for medical help as soon as possible.

                            Although rare, oxaprozin (Coxanto) can cause serious skin reactions called Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), or drug reaction with eosinophilia and systemic symptoms (DRESS). If you notice changes in your skin, such as rash, blisters, skin reddening, or skin peeling, stop using oxaprozin (Coxanto) and get medical attention right away.

                            risk-warning

                            Not for use during pregnancy

                            If you're pregnant, talk to your healthcare team first about the risk and benefits of oxaprozin (Coxanto) before using this medication. Oxaprozin (Coxanto) can cause harm to your unborn baby or complications during delivery if taken during the second half of pregnancy.

                            dosage

                            Oxaprozin (Coxanto) dosage forms

                            The average cost for 60 capsules of 300mg of Oxaprozin (Coxanto) is $328.03 with a free GoodRx coupon. This is 70.84% off the average retail price of $1124.99.
                            capsule
                            Capsule
                            DosageQuantityPrice as low asPrice per unit
                            300mg60 capsules$328.03$5.47

                            Typical dosing for Oxaprozin (Coxanto)

                            Your healthcare team will direct you to take the lowest dose of oxaprozin (Coxanto) for the shortest time needed to treat your symptoms.

                            • Osteoarthritis and rheumatoid arthritis: The typical dose is 1,200 mg by mouth once per day.

                            • Juvenile rheumatoid arthritis (children ages 6 to 16 years old): Your child's pediatrician will determine the dose based on your child's body weight. The typical dose will be either 600 mg, 900 mg, or 1,200 mg by mouth once per day. The maximum daily dose for children is 1,200 mg per day.

                            Note: Oxaprozin also comes as brand name (Daypro) and generic tablets. Oxaprozin tablets and oxaprozin capsules aren't interchangeable.

                            interactions

                            Interactions between Oxaprozin (Coxanto) and other drugs

                            Oxaprozin (Coxanto) may interact with certain medications or supplements. Always let your doctor and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking. The list below does not include all possible drug interactions with Oxaprozin (Coxanto). Please note that only the generic name of each medication is listed below.

                            Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

                            Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

                            Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

                            drug-cost

                            How much does Oxaprozin (Coxanto) cost?

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                            contraindications-icon

                            Oxaprozin (Coxanto) contraindications

                            Contraindications are specific health conditions or situations in which a person should not take a medication due to safety concerns. If you have any of the following conditions or if any of the following apply to you, let your healthcare provider know because Oxaprozin (Coxanto) will not be safe for you to take.
                            alternatives

                            What are alternatives to Oxaprozin (Coxanto)?

                            There are a number of medications that your doctor can prescribe in place of Oxaprozin (Coxanto). Compare a few possible alternatives below.
                            Oxaprozin (Coxanto)
                            Used for:
                            $328.03 Lowest GoodRx priceView Prices
                            Oxaprozin (Daypro)
                            Used for:

                            • Osteoarthritis

                            • Rheumatoid arthritis

                            • Juvenile rheumatoid arthritis

                            $41.99 Lowest GoodRx priceView Prices
                            Diclofenac
                            Used for:

                            • Mild to moderate pain

                            • Osteoarthritis

                            • Rheumatoid arthritis

                            • Ankylosing spondylitis (arthritis of the spine)

                            • Migraine attacks

                            • Menstrual cramps

                            $13.20 Lowest GoodRx priceView Prices
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                            Oxaprozin (Coxanto) images

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                            References

                            Best studies we found

                            Amneal Pharmaceuticals NY LLC. (2023). Oxaprozin tablet [package insert]. DailyMed.

                            Drugs and Lactation Database (LactMed®). (2024). Oxaprozin. National Institute of Child Health and Human Development.

                            National Heart, Lung, and Blood Institute. (2022). What is coronary artery bypass grafting?

                            View All References (4)

                            National Kidney Foundation. (2020). 10 signs you may have kidney disease.

                            Pfizer Laboratories Div Pfizer Inc. (2024). Daypro- oxaprozin tablet, film coated [package insert]. DailyMed.

                            Solubiomix, LLC. (2023). Coxanto- oxaprozin capsule [package insert]. DailyMed.

                            U.S. Food and Drug Administration. (2020). Nonsteroidal anti-inflammatory drugs (NSAIDs): Drug Safety Communication - Avoid use of NSAIDs in pregnancy at 20 weeks or later.

                            GoodRx Health has strict sourcing policies and relies on primary sources such as medical organizations, governmental agencies, academic institutions, and peer-reviewed scientific journals. Learn more about how we ensure our content is accurate, thorough, and unbiased by reading our editorial guidelines.
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