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Meperidine

Meperidine Side Effects

Kristianne Hannemann, PharmDAllison Gourley, PharmD
Reviewed by Kristianne Hannemann, PharmD, Allison Gourley, PharmD
Last reviewed on August 24, 2023

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Lightheadedness
  • Dizziness
  • Sleepiness
  • Nausea
  • Vomiting
  • Sweating

Less Common Side Effects

  • Weakness
  • Headache
  • Tremor
  • Confusion
  • Dry mouth
  • Constipation
  • Low blood pressure
  • Rash

Meperidine serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Allergic reaction: trouble breathing; hives; swelling in your face, lips, tongue, or throat
  • Dangerously slow breathing: trouble breathing; bluish-colored lips, fingers, or toes
  • Extremely low blood pressure: dizziness, lightheadedness, fainting
  • Accidentally taking too much (overdose): not responding to sound or touch, slowed breathing, extreme sleepiness, slow heartbeat, cold or clammy skin
  • Opioid withdrawal: anxiety, irritability, suicidal thoughts, restlessness, runny nose, yawning, sweating, chills, wide pupils, body aches, uncontrolled pain
  • Serotonin syndrome: fast heart rate, dizziness, sweating, flushing, shakiness, muscle stiffness, muscle twitching, uncoordinated movement, seizures, hallucinations
  • Seizures

Source: DailyMed

The following Meperidine side effects have also been reported

Side effects that you should report to your care team as soon as possible:

Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):

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