The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Common Side Effects
Immediate-release tablet
- Nausea (19%)
- Fever (14%)
- Sleepiness (9%)
- Vomiting (9%)
- Itching (8%)
- Headache (7%)
- Dizziness (7%)
Extended-release tablet
- Nausea (33%)
- Constipation (28%)
- Dizziness (18%)
- Sleepiness (17%)
- Vomiting (16%)
- Itching (15%)
- Headache (12%)
- Sweating (9%)
- Dry mouth (6%)
Less Common Side Effects
Immediate-release tablet
- Constipation
- Confusion
- Dry mouth
- Passing pass
- Feeling anxious
Extended-release tablet
- Diarrhea
- Trouble sleeping
- Tiredness
- Low appetite
- Stomach pain
Oxymorphone serious side effects
Contact your healthcare provider immediately if you experience any of the following.
- Dangerously slow breathing: trouble breathing; bluish-colored lips, fingers, or toes
- Accidentally taking too much (overdose): not responding to sound or touch, slowed breathing, slow heartbeat, extreme sleepiness, cold or clammy skin
- Opioid withdrawal: anxiety, suicidal thoughts, restlessness, irritability, runny nose, yawning, sweating, chills, wide pupils
- Serious allergic reaction: itchy, red rash (hives); shortness of breath; chest tightness; swelling of lips, tongue, throat, face, or eyes
Source: DailyMed
More on Oxymorphone side effects
The following Oxymorphone side effects have also been reported
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
Less common
Blurred vision
confusion
decreased urination
difficult or labored breathing
dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
fast, pounding, racing, or irregular heartbeat or pulse
headache
nervousness
pounding in the ears
rapid breathing
sunken eyes
sweating
swelling of the hands, ankles, or feet
thirst
tightness in the chest
unusual tiredness or weakness
wrinkled skin
Rare
Chest pain or discomfort
chills
cold sweats
confusion about identity, place, and time
decrease in consciousness
deep or fast breathing with dizziness
difficulty in passing urine (dribbling)
difficulty with sleeping
difficulty with swallowing
drowsiness to profound loss of consciousness
hoarseness
irregular, slow, or shallow breathing
irritability
irritation
joint pain, stiffness, or swelling
numbness of the feet, hands, and around the mouth
pale or blue lips, fingernails, or skin
puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
redness of the skin
restlessness
seeing, hearing, or feeling things that are not there
severe constipation
severe vomiting
stomach pain
shaking
trouble in holding or releasing urine
unusual drowsiness, dullness, or feeling of sluggishness
Incidence not known
Agitation
darkening of the skin
large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or genitals
loss of appetite
mental depression
overactive reflexes
poor coordination
seizures
shivering
talking or acting with excitement you cannot control
twitching
vomiting
Get emergency help immediately if any of the following symptoms of overdose occur:
Symptoms of overdose
Cold and clammy skin
constricted, pinpoint, or small pupils (black part of the eye)
decreased awareness or responsiveness
difficult or troubled breathing
irregular, fast, slow, or shallow breathing
low blood pressure or pulse
muscle weakness
pale or blue lips, fingernails, or skin
severe sleepiness or unusual drowsiness
very slow breathing
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common
Difficulty having a bowel movement
feeling of constant movement of self or surroundings
relaxed and calm
sensation of spinning
sleepiness
Less common
Belching
decreased weight
discouragement
excess air or gas in the stomach or bowels
feeling of warmth
feeling sad or empty
full or bloated feeling
indigestion
lack of appetite
loss of interest or pleasure
passing gas
pressure in the stomach
redness of the face, neck, arms, and occasionally, upper chest
stomach discomfort or upset
swelling of the abdominal or stomach area
tiredness
trouble concentrating
Rare
Blistering, crusting, irritation, itching, or reddening of the skin
cracked, dry, scaly skin
difficulty with thinking or concentrating
disturbed color perception
double vision
false or unusual sense of well-being
feeling jittery
halos around lights
loss of vision
night blindness
nightmares or unusually vivid dreams
overbright appearance of lights
sudden sweating
tunnel vision
welts
Incidence not known
Forgetfulness
loss of memory
problems with memory
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
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