Loratadine (Claritin) is an over-the-counter antihistamine. It's used to ease allergy symptoms, such as runny nose or watery eyes, in adults and children. Loratadine (Claritin) is taken by mouth, typically once daily. It's available in different formulations, such as tablets and oral solution. Loratadine (Claritin) is considered a non-drowsy medication because it's less likely to cause sleepiness than some other antihistamines, such as diphenhydramine (Benadryl). Other side effects of this medication include headache and tiredness.
Loratadine (Claritin) is an antihistamine. It blocks histamine, a natural chemical in your body that can cause allergy symptoms like itchy eyes, runny nose, and sneezing. In doing so, loratadine (Claritin) helps relieve allergy symptoms.
The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Contact your healthcare provider immediately if you experience any of the following.
Side effects that you should report to your care team as soon as possible:
Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):
Loratadine (Claritin) typically starts to relieve allergy symptoms within 1 to 3 hours. But it might take 8 to 12 hours before you experience the full effects of the medication. How quickly loratadine (Claritin) works might also depend on the dosage form (e.g., tablet, capsule, liquid, etc.) of loratadine (Claritin) you're taking. For example, loratadine (Claritin) tablets might work faster than the capsules.
In general, adults and children ages 6 years and older can take up to 10 mg of loratadine (Claritin) per day. And children ages 2 to under 6 years can take up to 5 mg of loratadine (Claritin) per day. Don't take more than the maximum recommended dose unless your healthcare professional specifically said it was safe to do so.
Yes, loratadine (Claritin) can make you feel drowsy (sleepy). But it's less likely to do so compared to other antihistamines, like diphenhydramine (Benadryl). This is because loratadine (Claritin) is a second-generation antihistamine that isn't as likely to cross into the brain compared to first-generation antihistamines. Let your primary care provider or pharmacist know if loratadine (Claritin) is making you too drowsy to go about your day. They might ask you to take it closer to bedtime or consider other options.
No, you should avoid taking loratadine (Claritin) and diphenhydramine (Benadryl) together, unless instructed by your primary care provider. Both medications are antihistamines and taking them together raises your risk of side effects, such as drowsiness, dry mouth, and dizziness. If you want to switch from loratadine (Claritin) to diphenhydramine (Benadryl), you'll typically need to wait 24 hours after your last dose of loratadine before starting diphenhydramine.
No, don't take loratadine (Claritin) and cetirizine (Zyrtec) together. They're both second-generation antihistamines. You'll likely have more side effects without additional allergy symptom relief by taking both. In general, both antihistamines work similarly well for treating allergy symptoms. Talk with your primary care provider if you've more questions about any specific antihistamine.
Loratadine (Claritin) is one of the options suggested by the American Academy of Dermatology Association to help ease itching and swelling from hives. Let your dermatologist or primary care provider know if you tend to get hives often. They can work with you to identify and avoid triggers. But get medical help right away if you experience trouble breathing or swelling of the tongue or in the mouth, along with hives. These are signs of a life-threatening allergic reaction that needs medical attention right away.
While you can take loratadine (Claritin) during pregnancy, it's not a first-choice option. The American College of Obstetricians and Gynecologists (ACOG) recommends chlorpheniramine as one of the preferred antihistamines for allergy during pregnancy. But this medication tends to cause more sleepiness compared to loratadine (Claritin). If you're pregnant, talk with your obstetrician about the risks and benefits of taking loratadine (Claritin) during pregnancy.
Loratadine (Claritin) can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.
Loratadine (Claritin) might make you sleepy, which can affect your ability to focus, think, or react. This side effect is more likely to happen if you drink alcohol while taking this medication or other medications that also cause sleepiness (e.g., opioids, certain anxiety medications, sleep medications). Don't drive or operate machinery until you know how this medication affects you.
Loratadine (Claritin) and other antihistamines can be found in many over-the-counter products. Taking too much loratadine (Claritin) or using more than one medication containing an antihistamine (including products used on the skin) can lead to an accidental overdose and cause serious side effects, such as seizures, hallucinations, or even death.
To prevent an accidental overdose, read package labels carefully. If you're not sure if a product has an antihistamine, ask your pharmacist. Don't start any new medications while taking loratadine (Claritin) without talking to your HCP or pharmacist first. If you think you or your loved one has taken too much medication, get medical help right away or contact a Poison Control Center at 1-800-222-1222.
Some chewable tablets and orally disintegrating tablets contain phenylalanine, a component of the artificial sweetener aspartame. If you have a genetic condition called phenylketonuria (PKU), taking these forms of loratadine (Claritin) can be dangerous for you. Read the manufacturer's label on the loratadine (Claritin) product you have to see if there's a warning for people with PKU. Ask your pharmacist if you're not sure a particular loratadine (Claritin) is safe for you. There are other formulations of the medication that might be safer for you.
The dose and direction of loratadine (Claritin) can differ depending on the manufacturer and formulation of the medication you have. This medication comes in pills and oral liquids, chewable tablets, and orally disintegrating tablets.
Be sure to follow the medication box for specific instructions. In general: