Inrebic

Used for Myelofibrosis

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FEDRATINIB treats bone marrow cancer. It works by blocking a protein that causes cancer cells to grow and multiply. This helps to slow or stop the spread of cancer cells. Compare JAK inhibitors.

What is Inrebic?

What should I tell my doctor?

They need to know if you have any of these conditions:

Blood clots
Cancer
Heart attack
Heart disease
Kidney disease
Liver disease
Low blood counts (white cells, platelets, or red blood cells)
Low levels of thiamine (vitamin B1) in the blood
Stroke
Tobacco use
An unusual or allergic reaction to fedratinib, other medications, foods, dyes, or preservatives
Pregnant or trying to get pregnant
Breastfeeding

How should I use this drug?

Take this medication by mouth with water. Take it as directed on the prescription label at the same time every day. You can take it with food or without food. If it upsets your stomach, take it with food. Keep taking it unless your care team tells you to stop.

Take a thiamine supplement every day while taking this medication. This medication can cause low levels of thiamine (vitamin B1) in your body. Serious adverse effects may occur if your levels are too low. Thiamine plays an important role in maintaining the health of your brain.

A special MedGuide will be given to you by the pharmacist with each prescription and refill. Be sure to read this information carefully each time.

Talk to your care team about the use of this medication in children. Special care may be needed.

What if I miss a dose?

If you miss a dose, skip it. Take your next dose at the normal time. Do not take extra or 2 doses at the same time to make up for the missed dose.

Where should I store this drug?

Keep out of the reach of children and pets.

Store between 15 and 30 degrees C (59 and 86 degrees F). Get rid of any unused medication after the expiration date.

To get rid of medications that are no longer needed or have expired:

Take the medication to a medication take-back program. Check with your pharmacy or law enforcement to find a location.
If you cannot return the medication, check the label or package insert to see if the medication should be thrown out in the garbage or flushed down the toilet. If you are not sure, ask your care team. If it is safe to put it in the trash, empty the medication out of the container. Mix the medication with cat litter, dirt, coffee grounds, or other unwanted substance. Seal the mixture in a bag or container. Put it in the trash.