The average list price of Jakafi (Ruxolitinib) is $17,150.00, but your out of pocket cost will likely be less if you have insurance. Jakafi is covered by some Medicare and insurance plans. This drug is also a limited distribution drug, meaning it is not available at retail pharmacies. Refer to the Key Takeaways for additional information on Jakafi and check our savings tips for other ways to reduce your cost. A generic version of Jakafi is not yet available. With the Patient Assistance Program from Good Days, contact the program to see how they can financially help you out.