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Hyoscyamine Coupon - Hyoscyamine 0.125mg sublingual tablet

hyoscyamine

Generic Levsin
Used for Cold Symptoms, Cystitis, Irritable Bowel Syndrome, Overactive Bladder, Parkinson's Disease, Peptic Ulcer

Hyoscyamine sulfate is an anticholinergic medication. It can ease symptoms of different conditions, including irritable bowel syndrome (IBS), stomach ulcers, and overactive bladder, in adults and children. Hyoscyamine is taken by mouth, typically every 4 hours. It's available in many dosage forms, including immediate-release tablets, sublingual tablets, and oral solution. Some side effects of hyoscyamine include dry mouth, sleepiness, and dizziness.

Reviewed by:
reviewerRobert Chad Hakim, PharmD, BCCCP
reviewerKristianne Hannemann, PharmD
Last reviewed on November 7, 2023
basics-icon

What is Hyoscyamine?

What is Hyoscyamine used for?

How Hyoscyamine works

Hyoscyamine belongs to the drug class known as anticholinergic medications. It works by blocking a chemical called acetylcholine from attaching to receptors (signaling proteins) in various parts of your body.

When does Hyoscyamine start working?Time passed since treatment started:
MINUTES
Initial effect
HOURS
Full effect
DAYS
WEEKS
MONTHS

Drug facts

Common BrandsLevsin, Hyosyne, Symax, Oscimin, NuLev
Drug ClassAnticholinergic
Controlled Substance ClassificationNot a controlled medication
Generic StatusLower-cost generic available
AvailabilityPrescription only
side-effects-icon

Side effects of Hyoscyamine

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Dry mouth
  • Trouble urinating
  • Constipation
  • Blurry vision
  • Dry eyes
  • Sleepiness
  • Dizziness
  • Headache
  • Flushing
  • Head intolerance

Less Common Side Effects

  • Fast heart rate
  • Diarrhea
  • Confusion
  • Short-term memory loss

Hyoscyamine serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Severe changes in mood, thoughts, or behavior: psychosis, agitation, hallucinations (seeing or hearing things that aren't there), confusion, euphoria
  • Irregular heartbeat: fainting, dizziness or lightheadedness, chest discomfort, shortness of breath, or fatigue

Source: DailyMed

The following Hyoscyamine side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Rare

Confusion (especially in the elderly)

dizziness, lightheadedness that continues, or fainting

eye pain

skin rash or hives

Incidence not known

Cough

difficulty with swallowing

fast irregular, pounding, or racing heartbeat or pulse

fever

hives or welts

hoarseness

irritation

itching skin

joint pain, stiffness, or swelling

puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue

redness of the skin

shortness of breath

skin rash

tightness in the chest

trouble with breathing

wheezing

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Constipation

decreased sweating

dryness of the mouth, nose, throat, or skin

Less common or rare

Bloated feeling

blurred vision

difficult urination

difficulty with swallowing

drowsiness

false sense of well-being

headache

increased sensitivity of eyes to light

loss of memory

nausea or vomiting

redness or other signs of irritation at the place of injection

trouble with sleeping

unusual tiredness or weakness

Incidence not known

Decreased interest in sexual intercourse

inability to have or keep an erection

loss in sexual ability, desire, drive, or performance

loss of taste

For patients using scopolamine:

After you stop using scopolamine, your body may need time to adjust. The length of time this takes depends on the amount of scopolamine you were using and how long you used it. During this period of time check with your doctor if you notice any of the following side effects:

Anxiety

irritability

nightmares

pupil of one eye is larger (patch only)

sensitivity of eyes to light (patch only)

trouble in sleeping

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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Pros and cons of Hyoscyamine

Pros

  • Works quickly to relieve symptoms
  • Comes in several different dosage forms (e.g., oral tablet, sublingual tablet, orally dissolving tablet, liquid)
  • Can be used in adults and children
  • Available as a lower-cost generic

Cons

  • Needs to be taken multiple times per day
  • Can have a lot of bothersome side effects (e.g., sleepiness, dizziness, dry mouth, trouble urinating, constipation)
  • Not known if it's safe for people who are pregnant or breastfeeding because it hasn't been studied
pharmacist-tips-icon

Pharmacist tips for Hyoscyamine

pharmacist
  • You can take hyoscyamine with or without food, but if it upsets your stomach, try taking it with food to help.
  • Hyoscyamine can cause dizziness and raise your risk for falls. Let you provider know if you're taking benzodiazepines, anxiety medications, or muscle relaxants. These medication can worsen sleepiness and confusion from hyoscyamine.
  • If you take antacids, take hyoscyamine before meals and the antacid after meals.
  • Hyoscyamine can cause your mouth to feel dry because it causes your body to make less saliva. Make sure to drink enough water when you're taking this medication.
  • Hyoscyamine can affect your ability to think, focus, and react. Don't drive, operate machinery, or do anything that requires concentration until you know how this medication affects you.
  • Hyoscyamine can cause your body to make less sweat. This can cause your body to overheat more easily in hot temperatures and make you more thirsty. Make sure to drink enough water and stay hydrated while taking this medication.
  • Different brands and formulations of this medication may be used in children of different ages. Discuss with your child's healthcare provider about which brand and dosage form is best for your child.

Tips on how to take hyoscyamine:

  • For the immediate-release and extended-release tablets: Swallow the tablets whole. Don't crush, chew, or split the tablets. If you're having trouble swallowing the tablets, talk to your provider about switching you to a different formulation of hyoscyamine.
  • For the sublingual tablet: Take the sublingual tablet by placing the tablet under your tongue and allow it to dissolve. Don't eat, drink, or smoke while it's dissolving. Also, you can swallow your saliva, but don't swallow the tablet.
  • For the dissolvable tablet (ODT):, make sure your hands are dry before handling the medication. Peel off the foil backing, and remove the tablet from the blister card. Don't try to push the tablet through the foil; this can damage the medication. Place the tablet on the tongue to let it dissolve, and swallow with saliva.

More tips for hyoscyamine liquid:

  • The oral drops contains 0.125 mg/mL and the elixir contains 0.125 mg/5 mL. Double check your bottle and the prescribed dose to avoid accidentally taking the wrong amount.
  • Store the medication bottle at room temperature and keep it in the original bottle to protect from light.
  • Make sure to only use a medication dose cup, syringe, or dropper from the pharmacy to measure out your dose. Don't use household spoons because they aren't accurate and might cause you to take the wrong dose.
faq-icon

Common questions about Hyoscyamine

No, hyoscyamine isn't a narcotic because it's not an opioid pain medication. Hyoscyamine is an anticholinergic medication.

No, hyoscyamine isn't a controlled substance.

No, weight loss or weight gain weren't reported side effects in people taking hyoscyamine. If you notice unexpected changes in your weight, contact your provider.

Hyoscyamine doesn't have any known interactions with omeprazole (Prilosec). But you should avoid taking antacids, like calcium carbonate (Tums) or Mylanta, with hyoscyamine because antacids can affect how well hyoscyamine is absorbed into your body. If your provider prescribed these medications together, take hyoscyamine before meals and take antacids after meals to avoid the interaction.

How quickly hyoscyamine works likely depends what formulation (e.g., liquid, tablet, sublingual tablet, etc.) of hyoscyamine you're taking and what condition you're taking hyoscyamine to treat. In general, hyoscyamine is a fast-acting medication that quickly gets into your blood after a dose. Talk to your provider if you're concerned with how well hyoscyamine is working for you.

Providers might prescribe hyoscyamine to help with diarrhea that's caused by certain conditions, such as irritable bowel syndrome (IBS). Hyoscyamine helps relax the muscles in the stomach and intestines, which slows gut movement, and the feeling of needing to go to the bathroom. But hyoscyamine isn't always a good choice for treating diarrhea. For example, diarrhea can also be a symptom of a block in the intestines. In this case, taking hyoscyamine can cause more harm. Don't take hyoscyamine for diarrhea unless directed by your provider.

Hyoscyamine might be able to help with gas, depending on the cause. For example, if you feel bloated because of IBS, your provider might prescribe hyoscyamine to help with the symptoms. If you have gas or feel bloated, talk with your provider first. They can help you figure out the cause and recommend an appropriate treatment.

It's recommended to avoid or limit alcohol while taking hyoscyamine because it can make sleepiness and dizziness worse. if avoiding alcohol isn't a possible option for you, talk to your provider about what's a safe amount of alcohol for you to drink while taking hyoscyamine.

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Risks and warnings for Hyoscyamine

Hyoscyamine can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.

Dizziness

Hyoscyamine can cause sleepiness, dizziness, and blurry vision. Don't drive or do any activity the requires a lot of attention until you know how this medication makes you feel.

Changes in mood, thoughts, or behaviors

  • Risk factors: Age 65 years or older | Mental health conditions

Hyoscyamine can sometimes change your mood, thoughts, or ability to think. It can cause symptoms such as confusion, memory loss, or feeling disoriented. It can also lead to agitation, seeing or hearing things that aren't really there (hallucinations), or euphoria. In serious cases, it can also lead to a coma. Typically, these symptoms go away in 12 to 48 hours after you stop hyoscyamine. Please let your provider know right away if you experience any changes to your mood, thoughts, or behaviors.

Faster heart rate

  • Risk factors: Heart problems | High blood pressure

If you have heart problems, such as heart failure, past heart attacks, or high blood pressure, let your provider know. Hyoscyamine can cause your heart rate to go up, which can worsen certain heart conditions. Let your provider know if you notice a change with your heart rate or feel symptoms such as a pounding or racing heart.

Changes to bodily functions

  • Risk factors: Age 65 years or older

Hyoscyamine can cause your autonomic nervous system, also known as involuntary functions of your body, to change. For example, you might experience the muscles of your gut slowing down, which can lead to constipation. Your body might produce less saliva or sweat, which can lead to dry mouth and feelings of thirst, and make it more likely for you to suffer a heat stroke. Hyoscyamine can also affect other functions, such as your heartbeat or vision. Let your provider know if you experience any changes to your bodily functions. If you have a fever, don't take hyoscyamine without asking your provider first.

Trouble urinating

Hyoscyamine should be used cautiously in people who have prostate problems, because it can worsen their condition and lead to difficulty urinating.

Caution in people with certain gut problems

If you've ever had a colostomy (or any similar procedures), let your provider know before you take hyoscyamine for diarrhea. Sometimes, diarrhea is a sign that you have a block in your gut, and taking hyoscyamine can be harmful.

If you think you have food poisoning, let your provide provider know before you take hyoscyamine. If you do, taking this medication can lead to a very dangerous problem called toxic megacolon.

Don't take hyoscyamine if you have severe ulcerative colitis. Large doses of hyoscyamine can slow the gut down to a stop. This can result in serious problems, like severe inflammation and swelling of the colon.

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Hyoscyamine dosage

The average cost for 30 sublingual tablets of 0.125mg of Hyoscyamine is $12.83 with a free GoodRx coupon. This is 60.13% off the average retail price of $32.18.
dropperDropper
DosageQuantityPrice as low asPrice per unit
15ml of 0.125mg/ml1 dropper$16.20$16.20
20ml of 0.125mg/ml1 dropper$19.61$19.61
ml of elixirMl of elixir
DosageQuantityPrice as low asPrice per unit
0.125mg/5ml150 ml$22.35$0.15
orally disintegrating tabOrally disintegrating tab
DosageQuantityPrice as low asPrice per unit
0.125mg30 orally disintegrating tabs$11.98$0.40
sublingual tabletSublingual tablet
DosageQuantityPrice as low asPrice per unit
0.125mg30 sublingual tablets$12.83$0.43
tabletTablet
DosageQuantityPrice as low asPrice per unit
0.125mg30 tablets$12.76$0.43

Typical dosage for Hyoscyamine

Hyoscyamine comes in many different formulations, including immediate-release (IR) tablet, extended-release tablets, orally disintegrating tablet, and liquid solutions. Follow the directions your provider gave for your specific hyoscyamine product.

Some examples include:

Hyoscyamine 0.125 mg immediate-release (IR) tablet:

  • Age 12 years or older: The typical dose is 1 to 2 tablets every 4 hours or as needed. The maximum dose is 12 tablets within a 24-hour period.
  • Age 2 to under 12 years (IR tablet and chewable tablet only): The typical dose is half a tablet to 1 tablet every 4 hours or as needed. The maximum dose is 6 tablets within a 24-hour period.

Hyoscyamine 0.375 mg extended-release tablets:

  • Age 12 years or older: The typical dose is 1 to 2 tablets by mouth every 12 hours. The maximum dose is 4 tablets within a 24-hour period.

Hyoscyamine 0.125 mg/1 mL oral solution drops:

  • Age 12 years or older: The typical dose is 1 to 2 mL by mouth every 4 hours or as needed. The maximum dose is 12 mL within a 24-hour period.
  • Age 2 to under 12 years: The typical dose is ¼ to 1 mL by mouth every 4 hours or as needed. Do not take more than 6 mL in 24 hours.
  • Age under 2 years: The dose depends on your child's body weight. In general, the typical dose ranges from a 4 drops to 8 drops by mouth every 4 hours or as needed.

There's also an injectable form that's used for people in the hospital who aren't able to take hyoscyamine by mouth.

interactions-icon

Interactions between Hyoscyamine and other drugs

Hyoscyamine may interact with certain medications or supplements. Always let your doctor and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking. The list below does not include all possible drug interactions with Hyoscyamine. Please note that only the generic name of each medication is listed below.

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking any of these medicines, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using medicines in this class with any of the following medicines is not recommended. Your doctor may decide not to treat you with a medication in this class or change some of the other medicines you take.

Using medicines in this class with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

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How much does Hyoscyamine cost?

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Levsin (brand)
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$11.98

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contraindications-icon

Hyoscyamine contraindications

Contraindications are specific health conditions or situations in which a person should not take a medication due to safety concerns. If you have any of the following conditions or if any of the following apply to you, let your healthcare provider know because Hyoscyamine will not be safe for you to take.

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What are alternatives to Hyoscyamine?

There are a number of medications that your doctor can prescribe in place of Hyoscyamine. Compare a few possible alternatives below.
Hyoscyamine
Used for:
$11.98Lowest GoodRx priceView prices
Used for:
$10.19Lowest GoodRx priceView prices
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Hyoscyamine images

White Round Pad And H - Hyoscyamine Sulfate 0.125mg Sublingual Tablet
This medicine is White, Round Sublingual Imprinted With "H" And "Pad".White Round Pad And H - Hyoscyamine Sulfate 0.125mg Sublingual Tablet
White Round P39 - Hyoscyamine Sulfate 0.125mg Sublingual Tablet
This medicine is White, Round Sublingual Imprinted With "P39".White Round P39 - Hyoscyamine Sulfate 0.125mg Sublingual Tablet
White Round Cl And 11 - Hyoscyamine Sulfate 0.125mg Sublingual Tablet
This medicine is White, Round Sublingual Imprinted With "11" And "Cl".White Round Cl And 11 - Hyoscyamine Sulfate 0.125mg Sublingual Tablet
Blue Round 113 And Ap - Hyoscyamine Sulfate 0.125mg Sublingual Tablet
This medicine is Blue, Round Sublingual Imprinted With "113" And "Ap".Blue Round 113 And Ap - Hyoscyamine Sulfate 0.125mg Sublingual Tablet
White Round Cl And 11 - Hyoscyamine Sulfate 0.125mg Sublingual Tablet
This medicine is White, Round Sublingual Imprinted With "11" And "Cl".White Round Cl And 11 - Hyoscyamine Sulfate 0.125mg Sublingual Tablet
Blue Round 105 And N - Hyoscyamine Sulfate 0.125mg Sublingual Tablet
This medicine is Blue, Round Sublingual Imprinted With "N" And "105".Blue Round 105 And N - Hyoscyamine Sulfate 0.125mg Sublingual Tablet

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References

Best studies we found

Acella Pharmaceuticals, LLC. (2023). Hyoscyamine sulfate ODT- hyoscyamine sulfate tablet, orally disintegrating [package insert]. DailyMed.

Acella Pharmaceuticals, LLC. (2023). Hyoscyamine sulfate SL- hyoscyamine sulfate tablet [package insert]. DailyMed.

BPI Labs LLC. (2023). Hyoscyamine sulfate injection, solution [package insert]. DailyMed.

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