Dexchlorpheniramine maleate, also known as brand name RyClora, is a first-generation antihistamine. It's prescribed for adults and children ages 2 years and older to treat symptoms of allergy or allergic reaction, like rash, itching, and sneezing. This medication works by blocking the effects of a chemical in the body called histamine. Dexchlorpheniramine (RyClora) comes as a cherry-flavored liquid that you take by mouth every 4 to 6 hours. It can cause side effects such as sleepiness, dizziness, and dry mouth.
Dexchlorpheniramine (RyClora) is a first-generation antihistamine. It blocks histamine, a natural chemical in your body that normally causes allergy symptoms. By blocking histamine, dexchlorpheniramine (RyClora) helps relieve allergy symptoms, such as runny nose, sneezing, and watery eyes.
The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Contact your healthcare provider immediately if you experience any of the following.
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
Less common or rare
Less common or rare with azatadine, cetirizine, clemastine, cyproheptadine, desloratadine, dexchlorpheniramine, diphenhydramine, or loratadine
Abdominal or stomach pain
burning
chills
clay-colored stools or dark urine
difficulty swallowing
dizziness
fast or irregular heartbeat
headache
prickly sensations
puffiness or swelling of the eyelids or around the eyes, face, lips or tongue
redness of skin
seizures
shortness of breath
skin rash
swelling
tightness in chest
tingling
unusual tiredness or weakness
Check with your doctor as soon as possible if any of the following side effects occur:
Symptoms of overdose
Clumsiness or unsteadiness
convulsions (seizures)
drowsiness (severe)
dryness of mouth, nose, or throat (severe)
feeling faint
flushing or redness of face
hallucinations (seeing, hearing, or feeling things that are not there)
shortness of breath or troubled breathing
trouble in sleeping
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common
Drowsiness
dry mouth, nose, or throat
gastrointestinal upset, stomach pain, or nausea
headache
increased appetite and weight gain
thickening of mucus
Less common or rare
Acid or sour stomach
belching
blurred vision or any change in vision
body aches or pain
clumsiness or unsteadiness
confusion (not with diphenhydramine)
congestion
difficult or painful urination
difficulty in moving
difficult or painful menstruation
dizziness (not with brompheniramine or hydroxyzine)
drowsiness (with high doses of desloratadine and loratadine)
dryness of mouth, nose, or throat
early menstruation
fast heartbeat
hoarseness
increased sensitivity of skin to sun
increased sweating
indigestion
loss of appetite
joint pain
muscle aching or cramping
muscle pains or stiffness
nightmares (not with azatadine, chlorpheniramine, cyproheptadine, desloratadine, hydroxyzine, or loratadine)
ringing or buzzing in ears
skin rash
swollen joints
stomach discomfort, upset or pain
tender swollen glands in neck
unusual excitement, nervousness, restlessness, or irritability
vomiting
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
Based on data of other first-generation antihistamines, dexchlorpheniramine (RyClora) will likely start to work 15 to 30 minutes after a dose. Its effects can last up to 6 hours after a dose. Talk with your healthcare team if you have more questions about what to expect after taking this medication.
No, dexchlorpheniramine (RyClora) is available by prescription from a healthcare professional only. Ask your primary care provider if an over-the-counter antihistamine is a good alternative choice to dexchlorpheniramine (RyClora).
Yes, dexchlorpheniramine (RyClora) is a prescription first-geneneration antihistamine used to treat several types of allergy conditions, such as seasonal and year-round allergies or mild skin symptoms of hives and angioedema.
Dexchlorpheniramine and chlorpheniramine are both first-generation antihistamines used to treat allergies. They have similar chemical structures, but there are some differences. Dexchlorpheniramine is more potent than chlorpheniramine, and is only available as a prescription oral solution. Chlorpheniramine, on the other hand, is available over-the-counter (OTC) in tablets and liquid form. However, dexchlorpheniramine can sometimes be found in combination OTC cold and allergy mediations, like Vanacof or Rymed. Ask a member of your care team if you have more questions on the differences between both medications.
More research is needed to understand how dexchlorpheniramine (RyClora) might affect a developing baby. Animal studies suggest that dexchlorpheniramine isn't likely to cause harm if taken by mothers during pregnancy. If you're pregnant, discuss with your obstetrician-gynecologist (OB-GYN) about the risks and benefits of taking this medication during pregnancy.
No, don't take dexchlorpheniramine (RyClora) while breastfeeding. This medication can get into breast milk and cause irritability and extreme drowsiness in breastfed babies. It also can dry up your breast milk supply. If you're breastfeeding, ask your obstetrician-gynecologist (OB-GYN) or prescriber about safer options to treat your condition.
Dexchlorpheniramine (RyClora) can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.
Accidentally taking too many antihistamines can be very dangerous, potentially leading to hallucinations, seizures, or even death. The risk is higher for children. Because dexchlorpheniramine (and other antihistamines) can be found in many over-the-counter cold and flu medications, it's important to check the labels of your medications to make sure you're not taking more than one antihistamine at a time.
Dexchlorpheniramine (RyClora) can make you sleepy, which can affect your ability to focus, think, or react. This side effect is more likely to happen or be more intense if you're an older adult, drink alcohol while taking dexchlorpheniramine (RyClora), or take other medications that cause sleepiness (e.g., opioids, benzodiazepines). Don't drive or operate machinery until you know how this medication affects you. It's best to avoid alcohol while taking dexchlorpheniramine (RyClora). Talk to your prescriber about possible interactions with other medications and how to manage them.
Make sure your care team knows about all of your medical conditions before starting dexchlorpheniramine (RyClora). Though this medication is an antihistamine, it also has anticholinergic effects, which can worsen the symptoms of many conditions. These conditions include glaucoma, hyperthyroidism, heart disease, high blood pressure, stomach ulcers, trouble urinating, and an enlarged prostate.
| Dosage | Quantity | Price as low as | Price per unit |
|---|---|---|---|
| 2mg/5ml | 473 ml | $67.28 | $0.14 |
Each 5 mL of RyClora contains 2 mg of dexchlorpheniramine.
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking any of these medicines, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
Using medicines in this class with any of the following medicines is not recommended. Your doctor may decide not to treat you with a medication in this class or change some of the other medicines you take.
Using medicines in this class with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
Contraindications are specific health conditions or situations in which a person should not take a medication due to safety concerns. If you have any of the following conditions or if any of the following apply to you, let your healthcare provider know because Dexchlorpheniramine (RyClora) will not be safe for you to take.