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Zymaxid vs. Biaxin

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Gatifloxacin (Zymaxid) and Clarithromycin (Biaxin) are both antibiotics, but they are used differently and belong to different classes. Gatifloxacin is a fluoroquinolone antibiotic used as eye drops to treat bacterial conjunctivitis (pink eye) in people aged 1 year and older. It works by blocking proteins bacteria need to reproduce and repair themselves. Clarithromycin, on the other hand, is a macrolide antibiotic taken orally to treat a variety of infections, including lung, sinus, strep throat, and skin infections. It stops bacteria from making certain proteins, preventing them from growing and surviving. Gatifloxacin is only available as eye drops, while Clarithromycin comes in immediate-release tablets, extended-release tablets, and liquid forms. Gatifloxacin is used multiple times a day for about a week, whereas Clarithromycin is typically taken once or twice a day for 7 to 14 days, depending on the infection. Common side effects of Gatifloxacin include eye irritation and changes in taste, while Clarithromycin can cause stomach pain, diarrhea, nausea, vomiting, and changes in taste. Additionally, Clarithromycin has many drug interactions and is not recommended for people with certain heart or liver conditions.

Gatifloxacin

(Zymaxid)

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Clarithromycin

 

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Summary for Zymaxid

Prescription only

Gatifloxacin (Zymaxid) is a fluoroquinolone antibiotic eye drop. It works well to treat pink eye caused by certain types of bacteria, but it doesn't treat pink eye caused by viruses. Gatifloxacin (Zymaxid) is approved for people ages 1 year and older. It's placed in the eye multiple times a day. Typically, treatment lasts about a week. Some of the more common side effects of gatifloxacin (Zymaxid) include eye irritation and changes in taste in your mouth.

Indications for Zymaxid

Pros and Cons for Zymaxid

Pros

  • Causes fewer serious side effects than oral antibiotics
  • Can be given to children age 1 year or older
  • Available as a lower-cost, generic form

Cons

  • Has to be used multiple times a day
  • Can cause temporary eye irritation after applying
  • Won't be able to treat pink eye caused by virus(es)

Common Side Effects for Zymaxid

  • Worsening of eye infection
  • Eye irritation
  • Eye pain
  • Changes the taste in your mouth

Warnings for Zymaxid

  • Allergic reactions
  • New infection

Summary for Biaxin

Prescription only

Clarithromycin (previously known by its brand name Biaxin) is an antibiotic that's used to treat a variety of bacterial infections in adults and children. It's available as a generic immediate-release tablet and solution taken twice per day and an extended-release tablet taken once per day. Side effects include a metallic or sour taste, nausea, vomiting, and diarrhea.

Indications for Biaxin

Pros and Cons for Biaxin

Pros

  • Treats many types of infections
  • Available as an extended-release tablet, immediate-release tablet, and a liquid
  • Available as a lower-cost generic

Cons

  • Can cause changes in taste, diarrhea, and stomach upset
  • Has many drug interactions
  • Not the best option if you have kidney problems
  • Not safe during pregnancy

Common Side Effects for Biaxin

Warnings for Biaxin

  • Severe allergic and skin reactions
  • Liver damage
  • Drug interactions
  • Heart rhythm problems (QT prolongation)
  • Possible higher risk of death from heart problems
  • Infectious diarrhea
  • Worsening of certain muscle problems (myasthenia gravis)

Prices with our coupons for Zymaxid vs. Biaxin

Price Card Drug Icon
Gatifloxacin1 eye dropper / 2.5ml of 0.5%
$35.54$124.99
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Price Card Drug Icon
Clarithromycin28 tablets / 500mg
$24.30$69.04
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