Key takeaways
Vyvanse (lisdexamfetamine) and Adderall (mixed amphetamine salts) are both stimulant medications used to treat ADHD (attention deficit-hyperactivity disorder). Vyvanse is also FDA approved for binge-eating disorder and Adderall is approved for narcolepsy. They’re both part of a group of stimulants called amphetamines. Vyvanse is a long-acting, or extended-release (ER), stimulant. Adderall comes in an immediate-release (IR) and ER form (Adderall XR). Vyvanse and Adderall XR are taken once a day usually, while Adderall IR may be taken 2 to 3 times a day. Vyvanse and Adderall have similar side effects such as low appetite, headache, and trouble sleeping. Both medications are controlled substances, which means they can lead to dependence and misuse. Taking them only as prescribed can help decrease these risks.
