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Trusopt vs. Xalatan

Dorzolamide is an eye drop medication used to treat high pressure in the eye in people with glaucoma or ocular hypertension. The dosage is 1 drop applied directly into the affected eye(s) three times per day. It's available as a generic only as the brand-name medication Trusopt has been discontinued. Dorzolamide is a sulfa medication, so it might not be the best choice if you have a serious sulfa allergy. Side effects include burning or stinging in the eye and a bitter taste in the mouth.

Treatment of high pressure in the eye in people with:

• Ocular hypertension
• Open-angle glaucoma

• Burning or stinging in the eye (33%)
• Bitter taste (25%)
• Bacterial eye infection (10-15%)
• Allergic reaction in the eye (10%)

• Severe allergic reactions
• Risk for eye infection (from contamination)
• Risk for swelling of the cornea

Latanoprost (Xalatan) is an eye drop medication. It's used in adults to treat conditions related to high pressure in the eye, such as glaucoma. It works as a prostaglandin to help with high eye pressure. The typical dosage is 1 drop in the affected eye(s) once each night. Side effects include feeling like there's something in the eye, burning, and stinging. Unopened bottles need to be refrigerated. But once opened, you keep the medication at room temperature. Latanoprost (Xalatan) is available as a brand-name and generic medication.

• Lowering pressure in the eye in people with open-angle glaucoma or ocular hypertension (high pressure in the eye)

• Feeling like there's something inside the eye (13%)
• Stinging (9%)
• Eye redness (8%)
• Blurry vision (8%)
• Itchy eye (8%)
• Burning (7%)
• Changes in eye color (7%)

• Darker eyes or eyelids
• Eyelash changes
• Eye inflammation
• Swelling of the retina (macular edema)
• Caution use in people with a history of a herpes eye infection
• Risk of bacterial eye infection when using contaminated medication
• Don't use while wearing soft contact lenses