Key takeaways
Metoprolol succinate (Toprol XL) and bisoprolol (Zebeta) are both beta blockers used to treat high blood pressure, but they have some key differences. Metoprolol succinate is also used to treat chest pain (angina) and to lower the risk of hospitalization and death in people with heart failure, while bisoprolol is primarily used for high blood pressure and is usually prescribed when first-choice medications aren't effective. Metoprolol succinate is an extended-release medication taken once daily with food, whereas bisoprolol can be taken with or without food. Common side effects of metoprolol succinate include tiredness and dizziness, while bisoprolol commonly causes headaches and fatigue. Both medications can hide symptoms of low blood sugar and should not be stopped suddenly without consulting your healthcare provider. Additionally, metoprolol succinate is available in a form that can be sprinkled on food, which can be helpful if you have trouble swallowing pills.
