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Tizanidine vs. Soma

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Tizanidine (Zanaflex) and carisoprodol (Soma) are both medications used to relax muscles, but they belong to different classes and have distinct uses and characteristics. Tizanidine is primarily used to treat muscle stiffness and rigidity, often associated with conditions like multiple sclerosis. It is available in both brand and generic forms and is typically taken up to three times a day. Common side effects include low blood pressure, dry mouth, and sleepiness. Carisoprodol, on the other hand, is a muscle relaxant used for short-term relief of muscle pain and discomfort. It is a Schedule IV controlled substance due to its potential for misuse and dependence, and it is usually taken four times a day for no more than 2 to 3 weeks. Carisoprodol can cause drowsiness, dizziness, and headaches. While both medications can cause sleepiness, carisoprodol has a higher risk of dependence and withdrawal symptoms compared to tizanidine. Additionally, carisoprodol should not be combined with alcohol or other habit-forming substances.

Tizanidine

(Zanaflex)

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Carisoprodol

(Soma)

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Summary for Tizanidine

Prescription only

Tizanidine, also known by its brand name Zanaflex, is a muscle relaxer. It's FDA approved to treat stiff, rigid muscles in adults. This medication comes as tablets and capsules that you take by mouth. The usual dosage is taken as needed, up to 3 times a day. It has side effects like dry mouth, sleepiness, dizziness, and constipation. Tizanidine (Zanaflex) is available as a generic and brand-name medication.

Indications for Tizanidine

Pros and Cons for Tizanidine

Pros

  • Taken as needed (up to 3 times a day) to help relax stiff or rigid muscles
  • Works within 1 to 2 hours
  • Also available as capsules that can be opened and sprinkled on applesauce
  • Not a controlled substance

Cons

  • Can cause dizziness, sleepiness, dry mouth, and low blood pressure
  • Interacts with many other medications, like birth control pills, ciprofloxacin, and opioids
  • Can cause withdrawal symptoms if you lower the dose or stop suddenly
  • Higher risk of side effects in older adults and people with kidney problems

Common Side Effects for Tizanidine

Warnings for Tizanidine

  • Low blood pressure
  • Sleepiness
  • Liver damage
  • Possible hallucinations
  • Withdrawal symptoms if stopped suddenly
  • Allergic reactions

Summary for Soma

Prescription only

Carisoprodol (Soma) is a muscle relaxant that's used to treat muscle pain and discomfort in people ages 16 to 64. The tablets are approved for short-term treatment only and should only be taken for up to 2 to 3 weeks. Researchers think the medication relaxes muscles by changing nerve activity in your nervous system. Carisoprodol (Soma) is a controlled substance because it has a risk for misuse and dependence. Common side effects include headaches, dizziness, and sleepiness.

Indications for Soma

  • Discomfort caused by painful muscle-related conditions (short-term only)

Pros and Cons for Soma

Pros

  • Works quickly (generally within 30 minutes) to relieve muscle pain and discomfort
  • Available in two different strengths
  • Available as a lower-cost generic

Cons

  • Not a first-choice option for muscle pain
  • Typically taken four times daily
  • Can be habit-forming
  • Unknown if it's safe for people younger than age 16 or older than age 65

Common Side Effects for Soma

  • Drowsiness (13-17%)
  • Dizziness (7-8%)
  • Headache (3-5%)

Warnings for Soma

  • Extreme sleepiness and trouble with concentration
  • Risk for misuse, dependence, and withdrawal
  • Seizures

Prices with our coupons for Tizanidine vs. Soma

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Tizanidine30 tablets / 4mg
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Carisoprodol60 tablets / 350mg
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