Key takeaways
Ropinirole (generic name) and Rasagiline (brand name Azilect) are both used to treat Parkinson's disease (PD), but they work differently and have different uses. Ropinirole is a dopamine agonist that mimics dopamine in the brain and is also used to treat restless legs syndrome (RLS). It comes in immediate-release and extended-release tablets. Rasagiline, on the other hand, is an MAO-B inhibitor that prevents the breakdown of dopamine, helping to control PD symptoms. You take it once a day. Ropinirole can cause side effects like nausea, sleepiness, and dizziness, while Rasagiline can cause headaches, joint pain, and a risk of serotonin syndrome if taken with certain medications. Additionally, Rasagiline requires you to avoid foods high in tyramine, like aged cheeses and cured meats, to prevent high blood pressure. Both medications are available in lower-cost generic forms.
